Epstein-Barr Virus Seroprevalence and Primary Infection at the University Hospital Luigi Vanvitelli of Naples from 2007 to 2017

被引：11

作者：

Franci, Gianluigi ^{[1
]}

Crudele, Valeria ^{[2
]}

Della Rocca, Maria Teresa ^{[1
]}

Melardo, Colombina ^{[1
]}

Chianese, Annalisa ^{[1
]}

Finamore, Emiliana ^{[2
]}

Bencivenga, Francesco ^{[3
]}

Astorri, Roberta ^{[4
]}

Vitiello, Mariateresa ^{[5
]}

Galdiero, Emilia ^{[6
]}

Galdiero, Massimiliano ^{[1
,2
]}

机构：

[1] Univ Campania Luigi Vanvitelli, Dept Expt Med, Via Costantinopoli 16, IT-80138 Naples, Italy

[2] Univ Hosp Luigi Vanvitelli Naples, Sect Microbiol & Virol, Naples, Italy

[3] Univ Campania Luigi Vanvitelli, Sect Hyg, Dept Expt Med, Naples, Italy

[4] Univ Molise, Dept Med & Hlth Sci Vincenzo Tiberio, Campobasso, Italy

[5] San Giovanni Dio Ruggi dAragona Hosp, Dept Clin Pathol, Virol Unit, Salerno, Italy

[6] Univ Naples Federico II, Dept Biol, Naples, Italy

来源：

INTERVIROLOGY | 2019年 / 62卷 / 01期

关键词：

Epstein-Barr virus; IgM; IgG; EBV nuclear antigen; Primary infection; AGE-SPECIFIC PREVALENCE; EPIDEMIOLOGY; INDIVIDUALS;

D O I：

10.1159/000496828

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in "Luigi Vanvitelli" University Hospital in the last 10 years. Our results showed that EBV seroprevalence in our geographical area was 65%. Seroprevalence increased gradually with age with no significant difference between females (49.42%) and males (50.58%). The seropositivity for primary infection was higher in patients about 5 years old, while seropositivity for past infection was predominant in patients of about 35 years old. These results underline that children in our country are still exposed to EBV. The development and the deeper use of an EBV vaccine in the early years of life could represent the solution for this infection. (C) 2019 S. Karger AG, Basel

引用

页码：15 / 22

页数：8

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