Design and Synthesis of Novel Pyrazolo[3,4-d]pyrimidin-1-yl piperidine Derivatives as Bruton's Tyrosine Kinase Inhibitors

被引：6

作者：

Park, Hyebin ^{[1
]}

Park, Chi Hoon ^{[2
,3
]}

Kang, Seung-Tae ^{[1
]}

Jeon, Jeong Hee ^{[2
]}

Archary, Raghavendra ^{[2
,3
]}

Lee, Joo-Youn ^{[2
]}

Kim, Pilho ^{[2
,3
]}

Jung, Heejung ^{[2
,3
]}

Yun, Chang-Soo ^{[2
,3
]}

Hwang, Jong Yeon ^{[2
,3
]}

Ryu, Do Hyun ^{[1
]}

Cho, Sung Yun ^{[2
,3
]}

机构：

[1] Sungkyunkwan Univ, Dept Chem, Suwon 440746, South Korea

[2] Korea Res Inst Chem Technol, Drug Discovery Div, Daejeon 305606, South Korea

[3] Univ Sci & Technol, Dept Med & Pharmaceut Chem, Daejeon 305550, South Korea

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2017年 / 38卷 / 02期

关键词：

Bruton's tyrosine kinase; BTK inhibitor; Pyrimidine derivative; Kinase inhibitor; Anticancer agent; X-LINKED AGAMMAGLOBULINEMIA; BTK; GENE; EXPRESSION; FAMILY; ITK; TEC;

D O I：

10.1002/bkcs.11065

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：278 / 281

页数：4

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