Controlled self-assembly of small molecule probes and the related applications in bioanalysis

被引：62

作者：

Li, Yongxin ^{[1
]}

Zhou, Huipeng ^{[1
]}

Chen, Jian ^{[1
]}

Shahzad, Sohail Anjum ^{[1
,3
]}

Yu, Cong ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

[3] COMSATS Inst Informat Technol, Dept Chem, Abbottabad 22060, Pakistan

来源：

BIOSENSORS & BIOELECTRONICS | 2016年 / 76卷

基金：

中国国家自然科学基金;

关键词：

Small molecule probe; Controlled self-assembly; Fluorescence; Bioanalysis; TURN-ON DETECTION; AGGREGATION-INDUCED-EMISSION; RATIOMETRIC FLUORESCENT-PROBE; ALKALINE-PHOSPHATASE ACTIVITY; LIGHT-UP PROBE; LABEL-FREE; EXCIMER FORMATION; ACETYLCHOLINESTERASE ACTIVITY; PERYLENE BISIMIDE; AQUEOUS-SOLUTION;

D O I：

10.1016/j.bios.2015.06.067

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Fluorescence spectroscopy is widely used in basic research, disease diagnosis, environmental monitoring, and the development of novel bioanalytical techniques. We mainly focus on the changes in fluorescence signal originated from the controlled self-assembly of small molecule probes, including aggregation caused quenching, aggregation induced emission, controlled turn-on of probe monomer emission, and the tunable monomer-excimer transition. Recent developments in the related bioanalytical techniques have been reviewed. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：38 / 53

页数：16

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