Applications of Nanopore Sensing in Detection of Toxic Molecules

被引:4
|
作者
Zhou Shuo [1 ]
Tang Peng [1 ]
Wang Yun-Jiao [1 ]
Wang Liang [1 ]
Wang De-Qiang [1 ]
机构
[1] Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Res Ctr Precis Med & Single Mol Diagnost, Chongqing 400714, Peoples R China
基金
中国国家自然科学基金;
关键词
Nanopore technology; Single-molecule sensing; Toxic molecules; Sensitivity; Selectivity; Review; LABEL-FREE; SINGLE-MOLECULE; BIOLOGICAL NANOPORES; PROTEIN; REAL; TIME; DNA; TETRACYCLINE; PEPTIDE; OLIGONUCLEOTIDE;
D O I
10.1016/S1872-2040(18)61089-8
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
As a novel analytical method, nanopore sensing is widely applied in many fields such as nucleic acids sequencing, protein/peptides analysis, detection of metal ions and biomacromolecules including virus, bacteria, etc. With the growing public concerns on dietary safety and public security, there has been a greater demand on the detection of toxic molecules. With high sensitivity and selectivity, nanopore sensing is considered as a more powerful assay, and has been reported in many research articles. Accordingly, this paper surveys the application of nanopore sensing in detection of toxic molecules.
引用
收藏
页码:826 / 835
页数:9
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