Fahr's Disease Presenting with Dementia at Onset: A Case Report and Literature Review

被引:13
作者
Calabro, Rocco Salvatore [1 ]
Spadaro, Letteria [1 ]
Marra, Angela [1 ]
Bramanti, Placido [1 ]
机构
[1] IRCCS Ctr Neurolesi Bonino Pulejo, I-98124 Messina, Italy
关键词
DIFFUSE NEUROFIBRILLARY TANGLES; CALCIFICATION DNTC; PRESENILE-DEMENTIA;
D O I
10.1155/2014/750975
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Fahr's disease (FD) is characterized by sporadic or familiar idiopathic calcification of the basal ganglia, dentate nuclei of the cerebellum, and centrum semiovale, mainly presenting with movement disorder, dementia, and behavioral abnormalities. We described a rare case of Fahr's disease presenting at onset only with behavioral and neuropsychological alterations, whose diagnosis was supposed only after a brain CT, which showed extensive bilateral calcifications in the dentate nuclei of the cerebellum and basal ganglia. Since the onset of Fahr's disease may be a dysexecutive syndrome with behavioral abnormalities, the clinical and radiological features are really important to do the appropriate diagnosis.
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页数:3
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