Drug Delivery with PEGylated MoS2 Nano-sheets for Combined Photothermal and Chemotherapy of Cancer

被引：1115
作者：
Liu, Teng [1 ,2 ]
Wang, Chao [1 ,2 ]
Gu, Xing [1 ,2 ]
Gong, Hua [1 ,2 ]
Cheng, Liang [1 ,2 ]
Shi, Xiaoze [1 ,2 ]
Feng, Liangzhu [1 ,2 ]
Sun, Baoquan [1 ,2 ]
Liu, Zhuang [1 ,2 ]
机构：
[1] Soochow Univ, Inst Funct Nano & Soft Mat FUNSOM, Suzhou 215123, Jiangsu, Peoples R China
[2] Soochow Univ, Collaborat Innovat Ctr Suzhou Nano Sci & Technol, Suzhou 215123, Jiangsu, Peoples R China
来源：
ADVANCED MATERIALS | 2014年 / 26卷 / 21期
关键词：
METAL DICHALCOGENIDE NANOSHEETS; GRAPHENE OXIDE; TUMOR VASCULATURE; THERAPY; NANOPARTICLES; NANOGRAPHENE; NANOTUBES; CHEMISTRY; CELLS;
D O I：
10.1002/adma.201305256
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
MoS2 nanosheets functionalized with poly ethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading capacities. Using doxorubicin as the model drug and taking advantages of the strong near-infrared absorbance of MoS2, combined photothermal and chemotherapy of cancer is realized in animal experiments, achieving excellent synergistic anti-tumor effect upon systemic administration.
引用
收藏
页码：3433 / 3440
页数：8
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