Update of the European guidelines for basal cell carcinoma management Developed by the Guideline Subcommittee of the European Dermatology Forum

被引:165
作者
Trakatelli, Myrto [1 ]
Morton, Colin [2 ]
Nagore, Eduardo [3 ]
Ulrich, Claas [4 ]
Del Marmol, Veronique [5 ]
Peris, Ketty [6 ]
Basset-Seguin, Nicole [7 ]
机构
[1] Papageorgiou Hosp, Dept Venereol & Dermatol 2, Thessaloniki, Greece
[2] Stirling Community Hosp, Dept Dermatol, Stirling FK8 2AU, Scotland
[3] Inst Valenciano Oncol, Dept Dermatol, Valencia, Spain
[4] Charite, Dept Dermatol, Skin Canc Ctr, D-13353 Berlin, Germany
[5] Univ Libre Bruxelles, Dept Dermatol, Hop Erasme, Brussels, Belgium
[6] Univ Aquila, Dept Dermatol, I-67100 Laquila, Italy
[7] Hop St Louis, Dept Dermatol, F-75017 Paris, France
关键词
NONMELANOMA SKIN-CANCER; MOHS MICROGRAPHIC SURGERY; AMINOLEVULINATE PHOTODYNAMIC THERAPY; TOPICAL METHYL AMINOLEVULINATE; IMIQUIMOD 5-PERCENT CREAM; MICROSCOPICALLY CONTROLLED EXCISION; HEART-TRANSPLANT RECIPIENTS; INGENOL MEBUTATE GEL; RECURRENCE RATES; RISK-FACTORS;
D O I
10.1684/ejd.2014.2271
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background European guidelines for the management of basal cell carcinoma (BCC) prepared by the former BCC subcommittee of the Guidelines Committee of the European Dermatology Forum (EDF) were published in 2006. Objectives To present updated guidelines that include consensual expert definitions on various BCC types, prognosis and risk factors for BCC as well as review recommendations for diagnosis and treatment reflecting current published evidence. Methods These guidelines (Si type) were prepared by the new BCC subgroup of the European Dermatology Forum (EDF)'s Guidelines Committee through extensive literature review (up to 2012) and expert experience; they were extensively discussed within the EDF subcommittee and approved by peer reviewers of the EDF. Results BCC is a common tumour with an incidence rising worldwide. Three major clinical types of BCC are recognized: nodular, superficial and morpheaform. Four histological subtypes are defined: superficial, nodular, infiltrative and morpheaform. On the basis of the risk of relapse, three prognosis groups have been identified: high, intermediate and low risk. According to these classifications and evidence-based evaluation of the therapeutic strategies available, a decision tree is proposed for the management of BCCs. Conclusions, The guidelines offer a useful tool that will help dermatologists to select the most appropriate treatment for individual patients.
引用
收藏
页码:312 / 329
页数:18
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