Molecular Imprinting Techniques Used for the Preparation of Biosensors

被引:197
作者
Erturk, Gizem [1 ]
Mattiasson, Bo [1 ,2 ]
机构
[1] CapSenze Biosyst AB, SE-22363 Lund, Sweden
[2] Lund Univ, Dept Biotechnol, SE-22369 Lund, Sweden
关键词
molecular imprinting; biomimetic sensors; bulk imprinting; surface imprinting; epitope imprinting; PROSTATE-SPECIFIC ANTIGEN; QUARTZ-CRYSTAL MICROBALANCE; PLASMON RESONANCE SENSOR; REAL-TIME; PROTEIN RECOGNITION; SOFT LITHOGRAPHY; SELECTIVE RECOGNITION; SENSITIVE DETECTION; SPR BIOSENSOR; SURFACE;
D O I
10.3390/s17020288
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Molecular imprinting is the technology of creating artificial recognition sites in polymeric matrices which are complementary to the template in their size, shape and spatial arrangement of the functional groups. Molecularly imprinted polymers (MIPs) and their incorporation with various transducer platforms are among the most promising approaches for detection of several analytes. There are a variety of molecular imprinting techniques used for the preparation of biomimetic sensors including bulk imprinting, surface imprinting (soft lithography, template immobilization, grafting, emulsion polymerization) and epitope imprinting. This chapter presents an overview of all of these techniques with examples from particular publications.
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页数:17
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