Broadband coherent Raman spectroscopy running at 24,000 spectra per second

被引：65

作者：

Hashimoto, Kazuki ^{[1
]}

Takahashi, Megumi ^{[1
]}

Ideguchi, Takuro ^{[2
]}

Goda, Keisuke ^{[1
,3
,4
]}

机构：

[1] Univ Tokyo, Dept Chem, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan

[2] Univ Tokyo, Res Ctr Spectrochem, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan

[3] Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA

[4] Japan Sci & Technol Agcy, Chiyoda Ku, 7 Yonbancho, Tokyo 1020076, Japan

来源：

SCIENTIFIC REPORTS | 2016年 / 6卷

关键词：

SCATTERING MICROSCOPY; IN-VIVO; TISSUE;

D O I：

10.1038/srep21036

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We present a Fourier-transform coherent anti-Stokes Raman scattering (FT-CARS) spectroscopy technique that achieves broadband CARS measurements at an ultrahigh scan rate of more than 20,000 spectra/s - more than 20 times higher than that of previous broadband coherent Raman scattering spectroscopy techniques. This is made possible by an integration of a FT-CARS system and a rapid-scanning retro-reflective optical path length scanner. To demonstrate the technique's strength, we use it to perform broadband CARS spectroscopy of the transient mixing dynamics of toluene and benzene in the fingerprint region (200-1500 cm(-1)) with spectral resolution of 10 cm(-1) at a record high scan rate of 24,000 spectra/s. Our rapid-scanning FT-CARS technique holds great promise for studying chemical dynamics and wide-field label-free biomedical imaging.

引用

页数：7

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