Assessment of Flavonoids as Rutin for Detoxification of T-2 Toxin

被引：9
作者：
El-Sawi, Nagwa M. [1 ]
Al-Seeni, Madeha N. [1 ]
机构：
[1] King Abdulaziz Univ, Fac Sci, Dept Biochem, Jeddah 2155142805, Saudi Arabia
来源：
JOURNAL OF APPLIED ANIMAL RESEARCH | 2009年 / 35卷 / 01期
关键词：
Mycotoxin T-2 toxin; trichothecene; rutin; antioxidants; serum; liver; hemoglobin;
D O I：
10.1080/09712119.2009.9706985
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
El-Sawi, N.M. and Al-Seeni, M.N. 2009. Assessment of flavonoids as rutin for detoxification of T-2 toxin. J. Appl. Anim. Res., 35: 57-60. To assess the efficacy of rutin, a flavonoid, for detoxifying T-2 toxin, 30 male albino rats were divided in 3 equal groups. Group I served as control. Rats in groups 2 and 3 were given 0.1 mg / kg bw T-2 toxin and those of group 3 were given 50 mg / kg rutin additionally. Toxin in liver tissue increased TBARs, SOD, GST, total lipids and decreased total thiol and catalase. Similarly there was increased lipid peroxide and decrease in total thiol, GST, hemoglobin and hematocrit value. All these were improved in group 3. The result suggest that rutin may be used as anti oxidant for T-2 toxin in liver of rat.
引用
收藏
页码：57 / 60
页数：4
相关论文
共 50 条
  • [1] T-2 TOXIN IMPAIRMENT OF MURINE RESPONSE TO SALMONELLA-TYPHIMURIUM - A HISTOPATHOLOGIC ASSESSMENT
    TAI, JH
    PESTKA, JJ
    MYCOPATHOLOGIA, 1990, 109 (03) : 149 - 155
  • [2] CHANGES INDUCED IN NEWBORN PIGLETS BY THE TRICHOTHECENE TOXIN T-2
    VANYI, A
    GLAVITS, R
    GAJDACS, E
    SANDOR, G
    KOVACS, F
    ACTA VETERINARIA HUNGARICA, 1991, 39 (1-2) : 29 - &
  • [3] T-2 toxin induces developmental toxicity and apoptosis in zebrafish embryos
    Yuan, Guogang
    Wang, Yimei
    Yuan, Xiaoyan
    Zhang, Tingfen
    Zhao, Jun
    Huang, Liuyu
    Peng, Shuangqing
    JOURNAL OF ENVIRONMENTAL SCIENCES, 2014, 26 (04) : 917 - 925
  • [4] Detection of T-2 Toxin in Wheat and Maize with a Portable Mass Spectrometer
    Maragos, Chris M.
    TOXINS, 2023, 15 (03)
  • [5] Identification and Apoptotic Potential of T-2 Toxin Metabolites in Human Cells
    Weidner, Maria
    Welsch, Tanja
    Huebner, Florian
    Schwerdt, Gerald
    Gekle, Michael
    Humpft, Hans-Ulrich
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, 60 (22) : 5676 - 5684
  • [6] Gene expression profiles in pregnant rats treated with T-2 toxin
    Sehata, S
    Kiyosawa, N
    Sakuma, K
    Ito, K
    Yamoto, T
    Teranishi, M
    Uetsuka, K
    Nakayama, H
    Doi, K
    EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, 2004, 55 (05) : 357 - 366
  • [7] Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol
    Zhang, Jie
    Zhang, Hua
    Liu, Shengli
    Wu, Wenda
    Zhang, Haibin
    TOXINS, 2018, 10 (05):
  • [8] Changes in antioxidant status of porcine ovarian granulosa cells after quercetin and T-2 toxin treatment
    Capcarova, Marcela
    Petruska, Peter
    Zbynovska, Katarina
    Kolesarova, Adriana
    Sirotkin, Alexander V.
    JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES, 2015, 50 (03) : 201 - 206
  • [9] The effects of T-2 toxin exposure on liver drug metabolizing enzymes in rabbit
    Guerre, P
    Eeckhoutte, C
    Burgat, V
    Galtier, P
    FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2000, 17 (12): : 1019 - 1026
  • [10] Anomericity of T-2 Toxin-glucoside: Masked Mycotoxin in Cereal Crops
    McCormick, Susan P.
    Kato, Takayuki
    Maragos, Chris M.
    Busman, Mark
    Lattanzio, Veronica M. T.
    Galaverna, Gianni
    Dall-Asta, Chiara
    Crich, David
    Price, Neil P. J.
    Kurtzman, Cletus P.
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2015, 63 (02) : 731 - 738
12345