C-Mannose derivatives as potent mimics of sialyl Lewis X

被引：44
|
作者：
Marron, TG
Woltering, TJ
WeitzSchmidt, G
Wong, CH
机构：
[1] Scripps Res Inst, DEPT CHEM, LA JOLLA, CA 92037 USA
[2] SANDOZ PHARMACEUT LTD, PRECLIN RES, CH-4002 BASEL, SWITZERLAND
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 50期
关键词：
D O I：
10.1016/S0040-4039(96)02124-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of five sialyl Lewis X mimetics was described. Mimetics 2 - 6 were easily synthesized from readily available starting materials. Mimics 4 and 6 showed activities five-fold better than sialyl Lewis X. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码：9037 / 9040
页数：4
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