Review of Possible Applications of Nanofibrous Mats for Wound Dressings

Skin is an important part of the human body. Its function is to control the body's homeostasis mechanism. If a skin injury occurs, it is of utmost importance to heal the skin as soon as possible. The currently available medical treatment system, however, has limited effectiveness on the regeneration of the structure and function of the injured skin, potentially causing wound infections and dehydration. The corresponding impact on the healing process may in the worst case also be fatal. To overcome these problems in wound dressing materials, nanofibrous mats are excellent candidates for wound treatment and management. Such wound dressings can be found in biomedical applications not only in drug delivery, but also as antibacterial and antimicrobial materials, and as materials for the regeneration and repair of tissue or organs. The large surface-area-to-volume ratio is one of the unique properties of nanofibrous mats. This paper gives a brief overview of possible materials and applications of nanofibrous mats for wound dressing.