Coexistence of virulence genes in methicillin-resistant Staphylococcus aureus clinical isolates

被引：7

作者：

Rossato, Adriana Medianeira ^{[1
]}

Reiter, Keli Cristine ^{[1
]}

d'Azevedo, Pedro Alves ^{[1
]}

机构：

[1] Univ Fed Ciencias Saude Porto Alegre, Lab Cocos Gram Posit, Porto Alegre, RS, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2018年 / 51卷 / 03期

关键词：

Coexistence of virulence genes; MRSA; Virulence genes; PANTON-VALENTINE LEUKOCIDIN; SOFT-TISSUE INFECTIONS; PATHOGENICITY ISLANDS; SUSCEPTIBILITY; TOXIN; SKIN;

D O I：

10.1590/0037-8682-0339-2017

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: The pathogenic versatility of Staphylococcus aureus is attributed to various virulence genes, including enterotoxins and hemolysins. Methods: Here, the virulence genes in 177 nosocomial MRSA strains in Porto Alegre, Brazil were detected by PCR. Results: The overall prevalence rates were as follows: sea, 4.5%; pvl, 18.6%; tst, 27.7%; hla, 87.6%; and hld, 90.4%. No strain contained all tested genes. However, there was frequent coexistence of tst with pvl and hla with hld (40.7% and 26.6%, respectively). Conclusions: Horizontal transfer of virulence genes is very common in S. aureus, as suggested by the frequent coexistence of several virulence genes.

引用

页码：361 / 363

页数：3

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