Liquid-crystalline behaviours of novel chitosan derivates containing singular and cholesteryl groups

被引:12
作者
Cong, Yue-Hua [2 ]
Wang, Wei [1 ]
Tian, Mei [1 ]
Meng, Fan-Bao [1 ]
Zhang, Bao-Yan [1 ]
机构
[1] Northeastern Univ, Ctr Mol Sci & Engn, Shenyang 110004, Peoples R China
[2] PolyTherics Ltd, London, England
关键词
chitosan; lyotropic liquid crystal; cholesteric; solubility; DRUG ENCAPSULATION; CARRIERS;
D O I
10.1080/02678290903006215
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of esters of chitosan with cholesteryl hexanoate and cholesteryl decanoate side chains were synthesised. These compounds had higher solubilities than chitosan itself and all formed cholesteric lyotropic liquid crystalline phases. They had enhanced mesogenic properties as compared with the parent polymer. We consider that these compounds may prove to be of value as vehicles for drug delivery.
引用
收藏
页码:455 / 460
页数:6
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