Transfusion Therapy in Children With Sickle Cell Disease

被引：9

作者：

Inati, Adlette ^{[1
,2
]}

Mansour, Anthony G. ^{[3
]}

Sabbouh, Toni ^{[3
]}

Amhez, Ghid ^{[3
]}

Hachem, Ahmad ^{[3
]}

Abbas, Hussein A. ^{[4
]}

机构：

[1] Lebanese Amer Univ, Dept Pediat, Beirut, Lebanon

[2] Univ Med Ctr, Rizk Hosp, Beirut, Lebanon

[3] Lebanese Amer Univ, Sch Med, Byblos, Lebanon

[4] Univ Texas MD Anderson Canc Ctr, Dept Mol & Cellular Oncol, Houston, TX 77030 USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2017年 / 39卷 / 02期

关键词：

sickle cell disease; blood transfusion indications; iron overload; ACUTE CHEST SYNDROME; ACUTE SPLENIC SEQUESTRATION; STROKE PREVENTION TRIAL; BLOOD-TRANSFUSION; IRON OVERLOAD; RECURRENT STROKE; ANEMIA; MANAGEMENT; ALLOIMMUNIZATION; MULTICENTER;

D O I：

10.1097/MPH.0000000000000645

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hydroxyurea, blood transfusions, and hematopoietic stem cell transplantation represent the 3 disease-modifying therapies in children with sickle cell disease (SCD). Blood transfusions play an increasingly important role in both prevention and management of SCD complications in this age group. This review will focus on the indications of blood transfusion in children with SCD and modalities of its administration. It will also highlight the complications of this life-saving therapy and ways of optimizing transfusion to minimize its associated risks.

引用

页码：126 / 132

页数：7

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