Different Calcium Phosphate Granules for 3-D Printing of Bone Tissue Engineering Scaffolds

被引：56

作者：

Seitz, Hermann ^{[1
,3
]}

Deisinger, Ulrike ^{[2
]}

Leukers, Barbara ^{[3
]}

Detsch, Rainer ^{[4
]}

Ziegler, Guenter ^{[2
,4
]}

机构：

[1] Univ Rostock, D-18059 Rostock, Germany

[2] Univ Bayreuth, Friedrich Baur Res Inst Biomat, D-95440 Bayreuth, Germany

[3] Res Ctr Caesar, D-53175 Bonn, Germany

[4] BioCer Entwicklungs GmbH, D-95447 Bayreuth, Germany

来源：

ADVANCED ENGINEERING MATERIALS | 2009年 / 11卷 / 05期

关键词：

CERAMICS; RESORPTION;

D O I：

10.1002/adem.200800334

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A study was conducted to transfer the 3-D printing technique to the fabrication of TCP and BCP ceramics and evaluate the influence of the granulate composition on the 3-D printed scaffolds. An aqueous solution of dextrin (20 wt.-%) and saccharose (2.5 wt.-%) were used as printing binder. The printing raster resolution and the thickness of the powder layers were selected as 0.29mm for the grid test parts and 0.26mm for the compression test parts. The granulates were characterized in terms of their particle size distribution using laser granulometry and their morphology. It was observed that spray-dried granulates could be fabricated from 'HA and TCP powders' and from a mixture of HA and TCP with the same composition of organic additives. The study also concluded that the mechanical properties of 3-D printed scaffolds can be adjusted by the design of the inner channel structure of the scaffolds.

引用

页码：B41 / B46

页数：6

共 13 条

[1] Formation of osteoclast-like cells on HA and TCP ceramics [J].