Locoregional treatment in oligometastatic breast cancer: A case report and review of treatment approaches in the era of cyclin inhibitors

被引:0
作者
Koh, Samantha Shui Yuan [1 ]
Pereira, Adriana Dantas Amaro [2 ]
de Paula, Bruno Henrique Rala [3 ]
Millen, Eduardo Camargo [4 ]
McAdam, Karen [5 ,6 ]
机构
[1] Univ Cambridge, Sch Clin Med, Cambridge, England
[2] Univ Vassouras, Vassouras, RJ, Brazil
[3] Univ Cambridge, Dept Oncol, Cambridge Biomed Campus, Cambridge, England
[4] Inst Oncoclin, Rio De Janeiro, Brazil
[5] Cambridge Univ Hosp Natl Hlth Serv NHS Fdn Trust, Dept Oncol, Cambridge, England
[6] North West Anglia NHS Fdn Trust, Peterborough City Hosp, Dept Oncol, Peterborough, England
来源
CURRENT PROBLEMS IN CANCER: CASE REPORTS | 2022年 / 5卷
关键词
Breast cancer; Hormone receptor positive; HER2; negative; Oligometastatic; Locoregional treatment; Cyclin inhibitors; Ribociclib; PRIMARY TUMOR; METASTASIS; DOCETAXEL; TRIAL; CELLS;
D O I
10.1016/j.cpccr.2022.100140
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Metastatic breast cancer is considered incurable. Data regarding how patients with oligometastatic breast cancer might best be treated is limited, with questions concerning the role of locoregional treatment, inclusive of surgery and radiotherapy, and local treatment to the metastatic site. Here we present a case of a 42-year-old woman with oligometastatic HR + /HER2- breast cancer, who achieved a complete radiological response for the metastatic site, after receiving ribociclib and undergoing breast surgery. We review the current evidence for locoregional treatment, and discuss the role of cyclin inhibitors in systemic treatment.
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页数:9
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