A simplified green chemistry approaches to synthesis of 2-substituted 1,2,3-triazoles and 4-amino-5-cyanopyrazole derivatives conventional heating versus microwave and ultrasound as ecofriendly energy sources

被引：25

作者：

Al-Zaydi, Khadijah M. ^{[1
]}

机构：

[1] King Abdulaziz Univ, Dept Chem, Girls Coll Educ, Jeddah 21533, Saudi Arabia

来源：

ULTRASONICS SONOCHEMISTRY | 2009年 / 16卷 / 06期

关键词：

Ecofriendly energy sources; Green chemistry; 2-Arylhydrazonocyano acetamides; 1,2,3-Triazole; Triazolopyrimidine; Pyrazol-4-amine; Microwave irradiation; Ultrasound irradiation; HETEROCYCLIC SYNTHESIS; 2-ARYLHYDRAZONONITRILES; ROUTE; PRECURSORS; REAGENTS;

D O I：

10.1016/j.ultsonch.2009.02.007

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Cyanoacetamides 3 were prepared via reacting ethyl cyanoacetate with benzylamine. Yields and reaction times needed for reaction completion at room temperature, by microwaves (mu omega) heating and under ultrasound (US) irradiations are compared. The formed cyanoacetamides were coupled with aromatic diazonium salts and the formed arylhydrazones were used as precursors to title triazoles and pyrazoles via reacting the former with hydroxylamine and chloroacetonitrile. Yields of products formed via conventional heating are compared with those of mu omega and US irradiation. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：805 / 809

页数：5

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