Cysteine and hydrophobic residues in CDR3 serve as distinct T-cell self-reactivity indices

被引:32
作者
Daley, Stephen R. [1 ,2 ]
Koay, Hui-Fern [3 ,4 ]
Dobbs, Kerry [5 ]
Bosticardo, Marita [5 ]
Wirasinha, Rushika C. [1 ,2 ]
Pala, Francesca [5 ]
Castagnoli, Riccardo [5 ]
Rowe, Jared H. [7 ,8 ]
de Bruin, Lisa M. Ott [9 ]
Keles, Sevgi [10 ]
Lee, Yu Nee [11 ]
Somech, Raz [11 ]
Holland, Steven M. [5 ]
Delmonte, Ottavia M. [5 ]
Draper, Debbie [5 ]
Maxwell, Sandra [5 ]
Niemela, Julie [6 ]
Stoddard, Jennifer [6 ]
Rosenzweig, Sergio D. [6 ]
Poliani, Pietro Luigi [12 ]
Capo, Valentina [13 ]
Villa, Anna [13 ,14 ]
Godfrey, Dale I. [3 ,4 ]
Notarangelo, Luigi D. [5 ]
机构
[1] Monash Univ, Monash Biomed Discovery Inst, Infect & Immun Program, Melbourne, Vic, Australia
[2] Monash Univ, Dept Biochem & Mol Biol, Melbourne, Vic, Australia
[3] Univ Melbourne, Peter Doherty Inst Infect & Immun, Dept Microbiol & Immunol, Melbourne, Vic, Australia
[4] Univ Melbourne, Australian Res Council Ctr Excellence Adv Mol Ima, Melbourne, Vic, Australia
[5] NIAID, Lab Clin Immunol & Microbiol, Div Intramural Res, 9000 Rockville Pike, Bethesda, MD 20892 USA
[6] NIH, Serv Immunol, Dept Lab Med, Ctr Clin, Bldg 10, Bethesda, MD 20892 USA
[7] Harvard Med Sch, Boston Childrens Hosp, Div Hematol Oncol, Boston, MA 02115 USA
[8] Harvard Med Sch, Dana Farber Canc Inst, Boston, MA 02115 USA
[9] Harvard Med Sch, Boston Childrens Hosp, Div Immunol, Boston, MA 02115 USA
[10] Necmettin Erbakan Univ, Meram Med Fac, Div Pediat Immunol & Allergy, Konya, Turkey
[11] Sheba Med Ctr, Edmond & Lily Safra Childrens Hosp, Immunol Serv, Tel Hashomer, Israel
[12] Univ Brescia, Dept Mol & Translat Med, Pathol Unit, Brescia, Italy
[13] Ist Ricovero & Cura Carattere Sci IRCCS San Raffa, San Raffaele Telethon Inst Gene Therapy, Milan, Italy
[14] CNR, Milan Unit, IRGB, Milan, Italy
基金
英国医学研究理事会; 美国国家卫生研究院;
关键词
DEFECTS;
D O I
10.1016/j.jaci.2019.03.022
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:333 / 336
页数:4
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