Concise Syntheses of Hyrtioreticulins C and D via a C-4 Pictet-Spengler Reaction: Revised Signs of Specific Rotations

被引：43

作者：

Abe, Takumi ^{[1
]}

Yamada, Koji ^{[1
]}

机构：

[1] Hlth Sci Univ Hokkaido, Fac Pharmaceut Sci, Ishikari, Hokkaido 0610293, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2017年 / 80卷 / 02期

关键词：

VIVO ANTITHROMBOTIC EVALUATION; TETRAHYDRO-BETA-CARBOLINES; CLAVICIPITIC ACID; INDOLE ALKALOIDS; A-C; BIOMIMETIC SYNTHESIS; MAJOR ENZYMES; L-TRYPTOPHAN; CIS; ACTIVATION;

D O I：

10.1021/acs.jnatprod.7b00008

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The first syntheses of hyrtioreticulins C and D via a Pictet Spengler reaction at the C-4 position of the indole rings are described. The synthesis proceeds in only two steps from commercially available starting materials. In this Communication, the structures of the natural products were confirmed. Furthermore, we revise the signs of the specific rotations of hyrtioreticulins C and D.

引用

页码：241 / 245

页数：5

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