1β,7β-Dihydroxydehydroabietic acid, a new biotransformation product of dehydroabietic acid by Aspergillus niger

被引:28
作者
Gouiric, SC
Feresin, GE
Tapia, AA
Rossomando, PC
Schmeda-Hirschmann, G
Bustos, DA
机构
[1] Univ Nacl San Juan, Fac Filosofia Humanidades & Artes, Inst Ciencias Basicas, RA-5400 San Juan, Argentina
[2] Univ Nacl San Juan, Fac Ingn, Inst Biotecnol, RA-5400 San Juan, Argentina
[3] Univ Nacl San Luis, Fac Quim Bioquim & Farm, Lab Quim Organ, RA-5700 San Luis, Argentina
[4] Univ Talca, Inst Quim Recursos Nat, Lab Quim Prod Nat, Talca, Chile
关键词
antibacterial activity; Aspergillus niger; biotransformation; dehydroabietic acid; 1; beta; 7 beta-dihydroxydehydroabietic acid;
D O I
10.1023/B:WIBI.0000023834.60165.79
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Microbial transformation of dehydroabietic acid by Aspergillus niger afforded the new derivative 1beta,7beta-dihydroxydehydroabietic acid and the known 1beta-hydroxy and 7beta-hydroxy derivatives. The structures were elucidated by spectroscopic methods. The compounds were assessed towards Gram (+) and Gram (-) bacteria and showed a weak antimicrobial effect.
引用
收藏
页码:281 / 284
页数:4
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