Food protein-induced enterocolitis syndrome: A case report of diarrhea with hypovolemic shock and methemoglobinemia

被引：3

作者：

Genere, L. ^{[1
]}

Pecciarini, N. ^{[1
,2
]}

Peretti, N. ^{[1
,2
]}

Villard, F. ^{[1
]}

Lachaux, A. ^{[1
,2
]}

机构：

[1] CHU Lyon, Hop Femme Mere Enfant, Hosp Civils Lyon, Serv Gastroenterol Hepatol & Nutr Pediat, 59 Blvd Pinel, F-69677 Bron, France

[2] Univ Claude Bernard Lyon 1, Fac Med Lyon Est, F-69003 Lyon, France

来源：

ARCHIVES DE PEDIATRIE | 2017年 / 24卷 / 01期

关键词：

CLINICAL-FEATURES; COWS MILK; ONDANSETRON; EXPERIENCE; ALLERGY; INFANTS;

D O I：

10.1016/j.arcped.2016.10.013

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We report on the case of a young infant with chronic diarrhea that worsened and turned into hypovolemic shock with methemoglobinemia. We underline and discuss the main features of food protein induced enterocolitis syndrome (FPIES). FPIES is a non-IgE-mediated food allergy involving tumor necrosis factor-alpha (TNF-alpha). Many triggering foods exist but cow's milk, as in the case reported herein, is one of the most frequent. It can start early or be delayed and start around the average age of 5 months. Symptoms are nonspecific with diarrhea and vomiting, but in the presence of methemoglobinemia, the diagnosis must be seriously considered. The oral food challenge remains the gold standard to confirm the diagnosis if there is still a doubt. Treatment of FPIES associates emergency treatment of acute dehydration with the prevention of relapses by avoiding the suspected protein. (C) 2016 Elsevier Masson SAS. All rights reserved.

引用

页码：28 / 32

页数：5

共 21 条

[1] Case report of methemoglobinemia in two patients with food protein-induced enterocolitis [J].