Red Jujube-Incorporated Gelatin Methacryloyl (GelMA) Hydrogels with Anti-Oxidation and Immunoregulation Activity for Wound Healing

被引：71

作者：

Huang, Jun ^{[1
]}

Chen, Long ^{[2
]}

Gu, Zhipeng ^{[1
]}

Wu, Jun ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Biomed Engn, Key Lab Sensing Technol & Biomed Instrument Guang, Guangzhou 510006, Guangdong, Peoples R China

[2] Guizhou Prov Peoples Hosp, Dept Orthoped, 83 Zhongshan East Rd, Guiyang 550000, Guizhou, Peoples R China

来源：

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY | 2019年 / 15卷 / 07期

关键词：

Red Jujube; Hybrid Hydrogel; Antioxidation; Immunoregulation; Wound Healing; INJECTABLE HYDROGEL; HYBRID HYDROGELS; IN-VITRO; TISSUE; CHITOSAN; DAMAGE;

D O I：

10.1166/jbn.2019.2815

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Red jujube has a long history of consumption for its excellent antioxidant activity and immunoregulation. In this study, red jujube-incorporated gelatin-methacryloyl (GelMA) hydrogels were developed using a programmed mixing method for wound healing. A series of evaluations, including structural characterization, antioxidant activity in vitro and in vivo, immunoregulation, and wound healing effects, were conducted. The results indicated that the introduction of red jujube equipped the GelMA hydrogel with antioxidation ability and light immune-stimulation. The wound healing results further confirmed that red jujube hybrid hydrogel could be a promising wound dressing material.

引用

页码：1357 / 1370

页数：14

共 51 条

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