Ionone glycosides from the roots of Rehmannia glutinosa

被引:33
作者
Liu, Yan-Fei
Liang, Dong
Luo, Huan
Hao, Zhi-You
Wang, Yan
Zhang, Chun-Lei
Ni, Gang
Chen, Ruo-Yun
Yu, De-Quan [1 ]
机构
[1] Chinese Acad Med Sci, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China
关键词
Rehmannia glutinosa; ionone glucoside; hepatoprotective; IRIDOID GLYCOSIDES; MONOTERPENE GLUCOSIDE; RADIX; REHMAPICROSIDE; REHMAIONOSIDES; CONSTITUENTS;
D O I
10.1080/10286020.2013.875011
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Four new ionone and ionone glycosides (1-4), and a new monoterpene (5), together with 10 known analogues (6-15), were isolated from the air-dried roots of Rehmannia glutinosa. The structures of these compounds were elucidated on the basis of spectroscopic data analysis. Furthermore, in in vitro assays, compound 3 (10M) exhibited moderate hepatoprotective activities against d-galactosamine-induced HL-7702 cell damage. [GRAPHICS] .
引用
收藏
页码:11 / 19
页数:9
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