Predictors of effective bilateral subthalamic nucleus stimulation for PD

被引：213
作者：
Charles, PD
Van Blercom, N
Krack, P
Lee, SL
Xie, J
Besson, G
Benabid, AL
Pollak, P
机构：
[1] Univ Grenoble 1, Dept Clin & Biol Neurosci, F-38043 Grenoble 9, France
[2] Vanderbilt Univ, Med Ctr, Nashville, TN USA
来源：
NEUROLOGY | 2002年 / 59卷 / 06期
关键词：
D O I：
10.1212/WNL.59.6.932
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
To identify factors predictive of effective bilateral subthalamic nucleus (STN) stimulation for PD with severe motor complications, pre- and postoperative Unified PD Rating Scale (UPDRS) scores were analyzed in a series of 54 patients who received bilateral STN stimulation. Younger age and levodopa responsiveness predict a favorable response to bilateral STN stimulation. For individual PD symptoms, those that improve with a supra-threshold dose levodopa challenge are likely to improve with stimulation.
引用
收藏
页码：932 / 934
页数：3
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