Surface Functionalized Selenium Nanoparticles for Biomedical Applications

被引:63
|
作者
Chaudhary, Savita [1 ]
Umar, Ahmad [2 ,3 ]
Mehta, S. K. [4 ,5 ]
机构
[1] Panjab Univ, Univ Inst Emerging Area Sci & Technol, Ctr Nanosci & Nanotechnol, Chandigarh 160014, India
[2] Najran Univ, Coll Arts & Sci, Dept Chem, Najran 11001, Saudi Arabia
[3] Najran Univ, Promising Ctr Sensors & Elect Devices, Najran 11001, Saudi Arabia
[4] Panjab Univ, Dept Chem, Chandigarh 160014, India
[5] Panjab Univ, Ctr Adv Studies Chem, Chandigarh 160014, India
关键词
Selenium Nanoparticles; Monolayer Structures; Biomedical Applications; Targeted Drug Delivery; DOXORUBICIN-INDUCED APOPTOSIS; PEROXIDASE-LIKE BEHAVIOR; KASHIN-BECK-DISEASE; GOLD NANOPARTICLES; IN-VITRO; ELEMENTAL SELENIUM; DRUG-DELIVERY; CANCER-CELLS; ALZHEIMERS-DISEASE; OXIDATIVE STRESS;
D O I
10.1166/jbn.2014.1985
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Selenium nanoparticles present an enhanced genetic actions and possess superior adsorptive capacity due to the interaction between the nanoparticles and NH, C=O, COO- and C-N groups of proteins. This review is focused on the biomedical applications of surafce funtionalized selenium nanoparticles. The engineering of exterior surface of the selenium nanoparticles has further emphasizing on the recent progresses in regulating monolayer structures for competent delivery of drugs and biomolecules. Crucial queries of transport, uptake, and clearance are discussed and illustrated through the prospects of selenium nanoparticles. The work presents an insight of how biomedical research can evolve with selenium nanoparticles and where we see the field is heading in the near future.
引用
收藏
页码:3004 / 3042
页数:39
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