Improvement in the stability of betanin by liposomal nanocarriers: Its application in gummy candy as a food model

被引:154
作者
Amjadi, Sajed [1 ,2 ]
Ghorbani, Marjan [3 ]
Hamishehkar, Hamed [4 ]
Roufegarinejad, Leila [1 ]
机构
[1] Islamic Azad Univ, Tabriz Branch, Dept Food Sci, Tabriz, Iran
[2] Tabriz Univ Med Sci, Biotechnol Res Ctr, Tabriz, Iran
[3] Tabriz Univ Med Sci, Stem Cell & Regenerat Med Inst, Tabriz, Iran
[4] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran
关键词
Betanin; Nanoparticle; Liposome; Encapsulation; Gummy candy; PHYSICOCHEMICAL PROPERTIES; ANTIOXIDANT ACTIVITY; CHEMICAL-STABILITY; PHENOLIC-COMPOUNDS; OXIDATIVE STRESS; BETALAINS; NANOLIPOSOMES; BIOAVAILABILITY; RELEASE; ENCAPSULATION;
D O I
10.1016/j.foodchem.2018.02.114
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Betanin is a red food pigment with health beneficial effects. Despite interest in the use of betanin, low bioaccessibility and oxidation limit its application. To overcome these restrictions, the betanin was loaded in liposomal nanocarriers with the encapsulation efficiency of 80.35 +/- 1%. To assess the efficiency of these nanocarriers, gummy candy was selected as a food model and its nutritional properties such as betanin stability and antioxidant activity were probed. The results showed that the betanin content and antioxidant activity of samples containing betanin-nanoliposomes were at least twice to those of samples containing free betanin. The tests show no differences in the sensory parameters of panelists for gummy candies fortified by betanin-loaded nanoliposomes compared to those fortified by betanin alone. As a result, the liposomal nanoparticles may be introduced as a suitable platform to stabilize and increase the bioavailability of betanin for applications in nutraceutical and medical fields.
引用
收藏
页码:156 / 162
页数:7
相关论文
共 40 条
[1]  
Afshin B, 2017, CURRENT DRUG TARGETS, V18, P1, DOI DOI 10.2174/1389450118666170508095250
[2]   Preparation and characterization of nano liposomes of Orthosiphon stamineus ethanolic extract in soybean phospholipids [J].
Aisha, Abdalrahim F. A. ;
Majid, Amin Malik Shah Abdul ;
Ismail, Zhari .
BMC BIOTECHNOLOGY, 2014, 14
[3]   Phosphatidylcholine-rutin complex as a potential nanocarrier for food applications [J].
Babazadeh, Afshin ;
Ghanbarzadeh, Babak ;
Hamishehkar, Hamed .
JOURNAL OF FUNCTIONAL FOODS, 2017, 33 :134-141
[4]   Influence of gelatin, starch, pectin and artificial saliva on the release of 11 flavour compounds from model gel systems [J].
Boland, AB ;
Buhr, K ;
Giannouli, P ;
van Ruth, SM .
FOOD CHEMISTRY, 2004, 86 (03) :401-411
[5]   Fruit candies enriched with grape skin powders: physicochemical properties [J].
Cappa, Carola ;
Lavelli, Vera ;
Mariotti, Manuela .
LWT-FOOD SCIENCE AND TECHNOLOGY, 2015, 62 (01) :569-575
[6]   Encapsulating betalains from Opuntia ficus-indica fruits by ionic gelation: Pigment chemical stability during storage of beads [J].
Carolina Otalora, Maria ;
Gregorio Carriazo, Jose ;
Iturriaga, Laura ;
Osorio, Coralia ;
Azucena Nazareno, Monica .
FOOD CHEMISTRY, 2016, 202 :373-382
[7]   Valorization of Nixtamalization wastewaters (Nejayote) by integrated membrane process [J].
Castro-Munoz, Roberto ;
Yanez-Fernandez, Jorge .
FOOD AND BIOPRODUCTS PROCESSING, 2015, 95 :7-18
[8]  
Charoen R, 2015, LEAF EXTRACT, V8, P3
[9]   The Stability, Sustained Release and Cellular Antioxidant Activity of Curcumin Nanoliposomes [J].
Chen, Xing ;
Zou, Li-Qiang ;
Niu, Jing ;
Liu, Wei ;
Peng, Sheng-Feng ;
Liu, Cheng-Mei .
MOLECULES, 2015, 20 (08) :14293-14311
[10]   The plasma bioavailability of nitrate and betanin from Beta vulgaris rubra in humans [J].
Clifford, Tom ;
Constantinou, Costas M. ;
Keane, Karen M. ;
West, Daniel J. ;
Howatson, Glyn ;
Stevenson, Emma J. .
EUROPEAN JOURNAL OF NUTRITION, 2017, 56 (03) :1245-1254