Development of small molecule inhibitors that target protein-protein interactions in a transcription factor

被引：0
|
作者：
Prive, Gilbert [1 ]
Kuntz, Douglas [1 ]
Poda, Gennady [2 ]
Isaac, Methvin [2 ]
Al-awar, Rima [2 ]
机构：
[1] Princess Margaret Canc Ctr, Toronto, ON, Canada
[2] Ontario Inst Canc Res, Toronto, ON, Canada
来源：
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES | 2018年 / 74卷
关键词：
D O I：
10.1107/S0108767318095958
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：A405 / A405
页数：1
相关论文
共 50 条
  • [1] Small-molecule inhibitors of protein-protein interactions
    Berg, Thorsten
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2008, 11 (05) : 666 - 674
  • [2] Small-molecule inhibitors of dimeric transcription factors: Antagonism of protein-protein and protein-DNA interactions
    Yap, Jeremy L.
    Chauhan, Jay
    Jung, Kwan-Young
    Chen, Lijia
    Prochownik, Edward V.
    Fletcher, Steven
    MEDCHEMCOMM, 2012, 3 (05) : 541 - 551
  • [3] A Screen to Identify Small Molecule Inhibitors of Protein-Protein Interactions in Mycobacteria
    Mai, Deborah
    Jones, Jennifer
    Rodgers, John W.
    Hartman, John L.
    Kutsch, Olaf
    Steyn, Adrie J. C.
    ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2011, 9 (03) : 299 - 310
  • [4] Targeting epigenetic protein-protein interactions with small-molecule inhibitors
    Linhares, Brian M.
    Grembecka, Jolanta
    Cierpicki, Tomasz
    FUTURE MEDICINAL CHEMISTRY, 2020, 12 (14) : 1305 - 1326
  • [5] Small-Molecule Inhibitors That Target Protein-Protein Interactions in the RAD51 Family of Recombinases
    Scott, Duncan E.
    Coyne, Anthony G.
    Venkitaraman, Ashok
    Blundell, Tom L.
    Abell, Chris
    Hyvoenen, Marko
    CHEMMEDCHEM, 2015, 10 (02) : 296 - 303
  • [6] Discovery of Small Molecule Inhibitors of Protein-Protein Interactions Using Combined Ligand and Target Score Normalization
    Casey, Fergal P.
    Pihan, Emilie
    Shields, Denis C.
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2009, 49 (12) : 2708 - 2717
  • [7] Identification of small molecule translesion synthesis inhibitors that target Rev1 protein-protein interactions
    Hadden, Matthew
    Sail, Vibhavari
    Thompson, Evrett
    Rizzo, Alessandro
    Korzhnev, Dmitry
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [8] Small-Molecule Inhibitors of Protein-Protein Interactions: How to Mimic a Protein Partner
    Fry, David C.
    CURRENT PHARMACEUTICAL DESIGN, 2012, 18 (30) : 4679 - 4684
  • [9] Small-molecule inhibitors of cancer-relevant protein-protein interactions
    Kiessling, A.
    Schust, J.
    Mueller, J.
    Sperl, B.
    Reindl, W.
    Hollis, A.
    Berg, T.
    ONKOLOGIE, 2008, 31 : 16 - 16
  • [10] Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
    Arkin, MR
    Wells, JA
    NATURE REVIEWS DRUG DISCOVERY, 2004, 3 (04) : 301 - 317
12345