Codon optimality and mRNA decay

被引:12
|
作者
Harigaya, Yuriko [1 ,2 ]
Parker, Roy [1 ,2 ]
机构
[1] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80303 USA
[2] Univ Colorado, Howard Hughes Med Inst, Boulder, CO 80303 USA
关键词
D O I
10.1038/cr.2016.127
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Recent evidence indicates that codon optimality is a broad determinant of mRNA stability. A study by Radhakrishnan et al. in Cell raises the possibility that the conserved DEAD-box protein Dhh1 underlies the phenomenon. © 2016 IBCB, SIBS, CAS All rights reserved.
引用
收藏
页码:1269 / 1270
页数:2
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