Gold Nanoparticles: Synthesis and Applications in Drug Delivery

被引：295

作者：

Khan, A. K. ^{[1
]}

Rashid, R. ^{[1
]}

Murtaza, G. ^{[2
]}

Zahra, A. ^{[1
]}

机构：

[1] COMSATS Inst Informat Technol, Dept Chem, Abbottabad 22060, Pakistan

[2] COMSATS Inst Informat Technol, Dept Pharm, Abbottabad 22060, Pakistan

来源：

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH | 2014年 / 13卷 / 07期

关键词：

Biosynthesis; Gold nanoparticles; Biomedical applications; Targeted drug delivery; Nanotechnology; CANCER-CELLS; MEDIATED SYNTHESIS; FACILE PREPARATION; BREAST-CANCER; CARCINOMA; APOPTOSIS; SYSTEMS; CARRIER;

D O I：

10.4314/tjpr.v13i7.23

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review is focused essentially on the synthesis and applications of gold nanoparticles in the field of medicine and targeted drug delivery. Nanotechnology has become one of the most interesting and advanced areas of research in this field. Among nanoparticles, gold nanoparticles demonstrate special advantages in this field due to their unique properties, small size and high surface area-to-volume ratio. These particles have been widely used in various biomedical applications and drug delivery systems due to their inert nature, stability, high dispersity, non-cytotoxicity and biocompatibility.

引用

页码：1169 / 1177

页数：9

共 45 条

[11] Sun light mediated synthesis of gold nanoparticles as carrier for 6-mercaptopurine: Preparation, characterization and toxicity studies in zebrafish embryo model [J].

Ganeshkumar, Moorthy ;

Sastry, Thotapalli Parvathaleswara ;

Kumar, Muniram Sathish ;

Dinesh, Murugan Girija ;

Kannappan, Sudalyandi ;

Suguna, Lonchin .

MATERIALS RESEARCH BULLETIN, 2012, 47 (09) :2113-2119

[12] Effect of gold nanoparticles on glutathione depletion-induced hydrogen peroxide generation and apoptosis in HL7702 cells [J].

Gao, Wen ;

Xu, Kehua ;

Ji, Lifei ;

Tang, Bo .

TOXICOLOGY LETTERS, 2011, 205 (01) :86-95

[13] A gold nanoparticle platform for the delivery of functional microRNAs into cancer cells [J].

Ghosh, Rajib ;

Singh, Lalithya C. ;

Shohet, Jason M. ;

Gunaratne, Preethi H. .

BIOMATERIALS, 2013, 34 (03) :807-816

[14] Gold Nanoparticles for Biology and Medicine [J].

Giljohann, David A. ;

Seferos, Dwight S. ;

Daniel, Weston L. ;

Massich, Matthew D. ;

Patel, Pinal C. ;

Mirkin, Chad A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (19) :3280-3294

[15] Monitoring human telomere DNA hybridization and G-quadruplex formation using gold nanorods [J].

Gou, Xin-Chun ;

Liu, Jun ;

Zhang, Hao-Li .

ANALYTICA CHIMICA ACTA, 2010, 668 (02) :208-214

[16] Biosynthesis of gold nanoparticles using a kind of flavonol: Dihydromyricetin [J].

Guo, Qingquan ;

Guo, Qiulan ;

Yuan, Juan ;

Zeng, Jinhua .

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2014, 441 :127-132

[17] Layer-by-layer assembled gold nanoparticles modified anode and its application in microbial fuel cells [J].

Guo, Wei ;

Pi, Yunqing ;

Song, Hong ;

Tang, Wen ;

Sun, Jianhui .

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2012, 415 :105-111

[18] The effect of cholesterol on protein-coated gold nanoparticle binding to liquid crystal-supported models of cell membranes [J].

Hartono, Deny ;

Hody ;

Yang, Kun-Lin ;

Yung, Lin-Yue Lanry .

BIOMATERIALS, 2010, 31 (11) :3008-3015

[19] Gold nanorods-bombesin conjugate as a potential targeted imaging agent for detection of breast cancer [J].

Heidari, Zahra ;

Sariri, Reyhaneh ;

Salouti, Mojtaba .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2014, 130 :40-46

[20] Gold nanoparticles: A paradigm shift in biomedical applications [J].

Khan, Mohammed S. ;

Vishakante, Gowda D. ;

Siddaramaiah, H. .

ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2013, 199 :44-58

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