Ouvrardianines A and B, Two New Norditerpenoid Alkaloids from Aconitum ouvrardianum

被引：5

作者：

Jing, Hong ^{[1
]}

Yang, Xiao-Dong ^{[1
]}

Zhao, Jing-Feng ^{[1
]}

Yang, Shu ^{[2
]}

Zhang, Hong-Bin ^{[1
]}

Li, Liang ^{[1
]}

机构：

[1] Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resources, Kunming 650091, Peoples R China

[2] Yunnan Agr Univ, Coll Fundamental & Informat Engn, Kunming 650201, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2009年 / 92卷 / 03期

关键词：

DITERPENOID ALKALOIDS; TANGUTICUM; EPISCOPALE;

D O I：

10.1002/hlca.200800311

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new norditerpenoid alkaloids, ouvrardianines A and B (1 and 2, resp.), together with eight known compounds, were isolated from Aconitum ouvrardianum. The structures of the new compounds were elucidated as (1 alpha,6 alpha,14 alpha,16 beta)-8-(acetyloxy)-13-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-aconit-19-en-14-yl benzoate (1) and (1 alpha,6 alpha,14 alpha,16 beta)-8-(acetyloxy)-20-formyl-13-hydroxy-1,6,16-trimethoxy-4-(methox ymethyl)aconitan-14-yl benzoate (2) on the basis of spectral analyses. The new compound 1 was found to contain the rare C(19)=N imine group.

引用

页码：514 / 519

页数：6

共 18 条

[1]

Chen D.L., 2002, W CHINA J PHARM SCI, V17, P326, DOI [10.13375/j.cnki.wcjps.2002.05.002, DOI 10.13375/J.CNKI.WCJPS.2002.05.002]

[2]

Chen S.Y., 1979, HUA HSUEH HSUEH PAO, V37, P15

[3] Acovulparine, a new norditerpene alkaloid from Aconitum vulparia [J].

Csupor, D ;

Forgo, P ;

Máthé, I ;

Hohmann, J .

HELVETICA CHIMICA ACTA, 2004, 87 (08) :2125-2130

[4]

HANUMAN JB, 1994, PHYTOCHEMISTRY, V36, P1527, DOI 10.1016/S0031-9422(00)89756-3

[5]

*I BOT CHIN AC SCI, 1979, FLOR REIP SIN, V27, P113

[6] PHARMACEUTICAL STUDIES ON ACONITUM ROOTS .9. STRUCTURE OF SENBUSINE-A, SENBUSINE-B AND SENBUSINE-C, DITERPENIC ALKALOIDS OF ACONITUM-CARMICHAELI ROOTS FROM CHINA [J].

KONNO, C ;

SHIRASAKA, M ;

HIKINO, H .

JOURNAL OF NATURAL PRODUCTS, 1982, 45 (02) :128-133

[7] A novel 19,21-secohetisan diterpenoid alkaloid from Aconitum tanguticum [J].

Li, L ;

Zhao, JF ;

Wang, YB ;

Zhang, HB .

HELVETICA CHIMICA ACTA, 2004, 87 (04) :866-868

[8] A new diterpenoid alkaloid from Aconitum episcopale [J].

Li, ZY ;

Zhao, JF ;

Yang, JH ;

Zhang, HB ;

Li, L .

HELVETICA CHIMICA ACTA, 2004, 87 (08) :2085-2087

[9]

Pelletier S.W., 1984, ALKALOIDS CHEM BIOL, P205

[10]

PELLETIER SW, 1979, HETEROCYCLES, V12, P779

← 1 2 →