Advances in pharmacotherapeutic management of common skin diseases in neonates and infants

被引:6
作者
Patrizi, Annalisa [1 ]
Neri, Iria [1 ]
Ricci, Giampaolo [2 ]
Cipriani, Francesca [2 ]
Ravaioli, Giulia Maria [1 ]
机构
[1] Univ Bologna, St Orsola Malpighi Hosp, Dept Expt Diagnost & Specialty Med, Dermatol, Via Massarenti 1, I-40138 Bologna, Italy
[2] Univ Bologna, St Orsola Malpighi Hosp, Dept Med & Surg Sci, Div Pediat, Bologna, Italy
关键词
Infantile hemangiomas; herpes simplex virus; varicella zoster virus; pyodermitis; impetigo; omphalitis; fasciitis; candidiasis; diaper dermatitis; napkin disease; atopic dermatitis; psoriasis; erythroderma; seborrhoeic dermatitis; erythema toxicum neonatorum; acrodermatitis enteropathica; biotin and vitamin B6 deficiency; HERPES-SIMPLEX-VIRUS; SOFT-TISSUE INFECTIONS; ATOPIC-DERMATITIS; SEBORRHEIC DERMATITIS; DIAPER DERMATITIS; HEMANGIOMAS; PROPRANOLOL; GUIDELINES; ACYCLOVIR; CHILDHOOD;
D O I
10.1080/14656566.2017.1316371
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Introduction: neonatal and infantile skin diseases are frequently encountered in the clinical practice and represent worldwide a socioeconomic issue. They encompass a wide range of acquired or congenital conditions, including infections, vascular lesions and inflammatory diseases and can present with different degrees of severity, leading in some cases to dramatic complications.Areas covered: In this paper we report the most recent evidences on the management of some common skin diseases in neonates and infants. Hemangiomas, viral, fungal and bacterial infections, omphalitis, atopic and seborrhoeic dermatitis, napkin disease will be treated and discussed.Expert opinion: The majority of the dermatologic alterations in neonates are physiological, transient and do not require any treatment, thus the parents can be reassured about the good prognosis. However, in some cases, serious conditions must be excluded. In particular neonatal and infantile infections should be promptly recognized and properly managed, to avoid severe complications. The therapeutic options include traditional and, although few, innovative medical treatments, which will be carefully taken into consideration by the expert Dermatologists and Paediatricians.
引用
收藏
页码:717 / 725
页数:9
相关论文
共 78 条
[41]   Interventions for impetigo [J].
Koning, Sander ;
van der Sande, Renske ;
Verhagen, Arianne P. ;
van Suijlekom-Smit, Lisette W. A. ;
Morris, Andrew D. ;
Butler, Christopher C. ;
Berger, Marjolein ;
van der Wouden, Johannes C. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2012, (01)
[42]   Acrodermatitis enteropathica and other nutritional diseases of the folds (intertriginous areas) [J].
Lakdawala, Nikita ;
Grant-Kels, Jane M. .
CLINICS IN DERMATOLOGY, 2015, 33 (04) :414-419
[43]   A Randomized, Controlled Trial of Oral Propranolol in Infantile Hemangioma [J].
Leaute-Labreze, C. ;
Hoeger, P. ;
Mazereeuw-Hautier, J. ;
Guibaud, L. ;
Baselga, E. ;
Posiunas, G. ;
Phillips, R. J. ;
Caceres, H. ;
Lopez Gutierrez, J. C. ;
Ballona, R. ;
Friedlander, S. F. ;
Powell, J. ;
Perek, D. ;
Metz, B. ;
Barbarot, S. ;
Maruani, A. ;
Szalai, Z. Z. ;
Krol, A. ;
Boccara, O. ;
Foelster-Holst, R. ;
Febrer Bosch, M. I. ;
Su, J. ;
Buckova, H. ;
Torrelo, A. ;
Cambazard, F. ;
Grantzow, R. ;
Wargon, O. ;
Wyrzykowski, D. ;
Roessler, J. ;
Bernabeu-Wittel, J. ;
Valencia, A. M. ;
Przewratil, P. ;
Glick, S. ;
Pope, E. ;
Birchall, N. ;
Benjamin, L. ;
Mancini, A. J. ;
Vabres, P. ;
Souteyrand, P. ;
Frieden, I. J. ;
Berul, C. I. ;
Mehta, C. R. ;
Prey, S. ;
Boralevi, F. ;
Morgan, C. C. ;
Heritier, S. ;
Delarue, A. ;
Voisard, J-J .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (08) :735-746
[44]   Infantile haemangioma: Part I. Pathophysiology, epidemiology, clinical features, life cycle and associated structural abnormalities [J].
Leaute-Labreze, C. ;
Prey, S. ;
Ezzedine, K. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2011, 25 (11) :1245-1253
[45]   Atopic dermatitis: understanding the disease and its management [J].
Levy, M. L. .
CURRENT MEDICAL RESEARCH AND OPINION, 2007, 23 (12) :3091-3103
[46]  
Levy ML, 2014, NEONATAL DERMATOLOG, P265
[47]   Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis [J].
Lyu, Xin ;
Zhao, Chen ;
Yan, Zhi-min ;
Hua, Hong .
DRUG DESIGN DEVELOPMENT AND THERAPY, 2016, 10 :1161-1171
[48]  
Madiraca D, 2016, ACTA DERMATOVENER CR, V24, P175
[49]   Rapidly Involuting Congenital Hemangioma with Fetal Involution [J].
Maguiness, Sheilagh ;
Uihlein, Lily Changchien ;
Liang, Marilyn G. ;
Kozakewich, Harry ;
Mulliken, John B. .
PEDIATRIC DERMATOLOGY, 2015, 32 (03) :321-326
[50]   Propranolol and Infantile Hemangiomas Four Years Later: A Systematic Review [J].
Marqueling, Ann L. ;
Oza, Vikash ;
Frieden, Ilona J. ;
Puttgen, Katherine B. .
PEDIATRIC DERMATOLOGY, 2013, 30 (02) :182-191