T cell responses in acute measles

被引：26
作者：
van Els, CACM
Nanan, R
机构：
[1] Natl Inst Publ Hlth & Environm, Lab Vaccine Res, NL-3721 MA Bilthoven, Netherlands
[2] Univ Wurzburg, Childrens Hosp, Wurzburg, Germany
来源：
VIRAL IMMUNOLOGY | 2002年 / 15卷 / 03期
关键词：
D O I：
10.1089/088282402760312322
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Immune containment of measles virus (MV) infection has long been a focus of interest for investigators. An emerging theme is that MV immunity is conferred by appropriately polarized antiviral CD4(+) and CD8(+) T cell populations. Recent technological advances permit the analysis of the composition and dynamics of these CD4(+) and CD8(+) T cell responses at the single cell level, and of the molecular events responsible for their induction. Novel insights into these issues for measles are discussed in the light of their importance for the development of an improved vaccine.
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收藏
页码：435 / 450
页数：16
相关论文
共 129 条
[41]   Measles virus infects human dendritic cells and blocks their allostimulatory properties for CD4(+) T cells [J].
Grosjean, I ;
Caux, C ;
Bella, C ;
Berger, I ;
Wild, F ;
Banchereau, J ;
Kaiserlian, D .
JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (06) :801-812
[42]  
HAMMOND SA, 1995, J IMMUNOL, V154, P6140
[43]   CD8+ T cell effector mechanisms in resistance to infection [J].
Harty, JT ;
Tvinnereim, AR ;
White, DW .
ANNUAL REVIEW OF IMMUNOLOGY, 2000, 18 :275-308
[44]   A measles virus glycoprotein-derived human CTL epitope is abundantly presented via the proteasomal-dependent MHC class I processing pathway [J].
Herberts, CA ;
Stittelaar, KJ ;
van der Heeft, E ;
van Ganns-van den Brink, J ;
Poelen, MCM ;
Roholl, PJM ;
van Alphen, LJW ;
Melief, CJM ;
de Jong, APJM ;
van Els, CACM .
JOURNAL OF GENERAL VIROLOGY, 2001, 82 :2131-2142
[45]   Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory [J].
Homann, D ;
Teyton, L ;
Oldstone, MBA .
NATURE MEDICINE, 2001, 7 (08) :913-919
[46]   STRICTLY TRANSPORTER OF ANTIGEN PRESENTATION (TAP)-DEPENDENT PRESENTATION OF AN IMMUNODOMINANT CYTOTOXIC T-LYMPHOCYTE EPITOPE IN THE SIGNAL SEQUENCE OF A VIRUS PROTEIN [J].
HOMBACH, J ;
PIRCHER, H ;
TONEGAWA, S ;
ZINKERNAGEL, RM .
JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 182 (05) :1615-1619
[47]   Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry (Reprinted from Science, vol 255, March 6, 1992) [J].
Hunt, Donald F. ;
Henderson, Robert A. ;
Shabanowitz, Jeffrey ;
Sakaguchi, Kazuyasu ;
Michel, Hanspeter ;
Sevilir, Noelle ;
Cox, Andrea L. ;
Appella, Ettore ;
Engelhard, Victor H. .
JOURNAL OF IMMUNOLOGY, 2007, 179 (05) :2669-2671
[48]   Measles virus-specific immunoglobulin G isotype immune response in early and late infections [J].
Isa, MB ;
Martínez, L ;
Giordano, M ;
Zapata, M ;
Passeggi, C ;
De Wolff, MC ;
Nates, S .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (01) :170-174
[49]   HLA CLASS-II-RESTRICTED PRESENTATION OF CYTOPLASMIC MEASLES-VIRUS ANTIGENS TO CYTO-TOXIC T-CELLS [J].
JACOBSON, S ;
SEKALY, RP ;
JACOBSON, CL ;
MCFARLAND, HF ;
LONG, EO .
JOURNAL OF VIROLOGY, 1989, 63 (04) :1756-1762
[50]   Ex vivo analysis of cytotoxic T lymphocytes to measles antigens during infection and after vaccination in Gambian children [J].
Jaye, A ;
Magnusen, AF ;
Sadiq, AD ;
Corrah, T ;
Whittle, HC .
JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (11) :1969-1977
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