T cell responses in acute measles

被引：27
作者：
van Els, CACM
Nanan, R
机构：
[1] Natl Inst Publ Hlth & Environm, Lab Vaccine Res, NL-3721 MA Bilthoven, Netherlands
[2] Univ Wurzburg, Childrens Hosp, Wurzburg, Germany
来源：
VIRAL IMMUNOLOGY | 2002年 / 15卷 / 03期
关键词：
D O I：
10.1089/088282402760312322
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Immune containment of measles virus (MV) infection has long been a focus of interest for investigators. An emerging theme is that MV immunity is conferred by appropriately polarized antiviral CD4(+) and CD8(+) T cell populations. Recent technological advances permit the analysis of the composition and dynamics of these CD4(+) and CD8(+) T cell responses at the single cell level, and of the molecular events responsible for their induction. Novel insights into these issues for measles are discussed in the light of their importance for the development of an improved vaccine.
引用
收藏
页码：435 / 450
页数：16
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