The Impact of Prior Infection and Age on Antibody Persistence After Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine

被引：13

作者：

Fraley, Elizabeth ^{[1
]}

LeMaster, Cas ^{[1
]}

Khanal, Santosh ^{[1
]}

Banerjee, Dithi ^{[1
]}

Pastinen, Tomi ^{[1
]}

Grundberg, Elin ^{[1
]}

Selvarangan, Rangaraj ^{[1
]}

Bradley, Todd ^{[1
]}

机构：

[1] Childrens Mercy Kansas City, 2401 Gillham Rd, Kansas City, MO 64108 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2022年 / 75卷 / 01期

关键词：

SARS; CoV; 2; COVID; 19; Antibody response; Vaccine;

D O I：

10.1093/cid/ciab850

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Determining the duration of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines is critical for informing the timing of booster immunization. Many genetic and environmental factors could influence both the magnitude and persistence of the antibody response. Here, we showed that SARS-CoV-2 infection before vaccination and age affected the decay of antibody responses to the SARS-CoV-2 messenger RNA vaccine.

引用

页码：E902 / E904

页数：3

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