3D Printed Functional and Biological Materials on Moving Freeform Surfaces

被引:188
作者
Zhu, Zhijie [1 ]
Guo, Shuang-Zhuang [1 ]
Hirdler, Tessa [2 ]
Eide, Cindy [2 ]
Fan, Xiaoxiao [1 ]
Tolar, Jakub [2 ,3 ,4 ,5 ]
McAlpine, Michael C. [1 ]
机构
[1] Univ Minnesota, Dept Mech Engn, 111 Church St SE, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Dept Pediat, Div Blood & Marrow Transplantat, Minneapolis, MN 55455 USA
[3] Univ Minnesota, Ctr Genome Engn, Minneapolis, MN 55455 USA
[4] Univ Minnesota, Dept Pediat, Stem Cell Inst, Minneapolis, MN 55455 USA
[5] Univ Minnesota, Asan Minnesota Inst Innovating Transplantat, Minneapolis, MN 55455 USA
基金
美国国家卫生研究院;
关键词
3D printing; bioprinting; feedback control; robotics; wireless electronics; NANOCOMPOSITES;
D O I
10.1002/adma.201707495
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Conventional 3D printing technologies typically rely on open-loop, calibrate-then-print operation procedures. An alternative approach is adaptive 3D printing, which is a closed-loop method that combines real-time feedback control and direct ink writing of functional materials in order to fabricate devices on moving freeform surfaces. Here, it is demonstrated that the changes of states in the 3D printing workspace in terms of the geometries and motions of target surfaces can be perceived by an integrated robotic system aided by computer vision. A hybrid fabrication procedure combining 3D printing of electrical connects with automatic pick-and-placing of surface-mounted electronic components yields functional electronic devices on a free-moving human hand. Using this same approach, cell-laden hydrogels are also printed on live mice, creating a model for future studies of wound-healing diseases. This adaptive 3D printing method may lead to new forms of smart manufacturing technologies for directly printed wearable devices on the body and for advanced medical treatments.
引用
收藏
页数:8
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