The clinical value of dynamic contrast-enhanced magnetic resonance imaging at 3.0T to detect prostate cancer

被引：9
作者：
Zhang, Xuhui [1 ]
Quan, Xianyue [1 ]
Lu, Shilong [1 ]
Huang, Fanheng [1 ]
Yang, Jianming [1 ]
Chan, Queenie [2 ]
Lin, Ting [1 ]
机构：
[1] Southern Med Univ, Dept Radiol, Zhujiang Hosp, Guangzhou 510282, Guangdong, Peoples R China
[2] Philips Healthcare, Hong Kong, Hong Kong, Peoples R China
来源：
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2014年 / 42卷 / 05期
关键词：
Prostate cancer; T2WI; DCE-MRI; Gleason score; 3; T; MRI; LOCALIZATION;
D O I：
10.1177/0300060514541827
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Objective: To compare dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and T-2-weighted imaging (T2WI) at 3.0T for detection of prostate cancer. Methods: Patients with elevated prostate-specific antigen underwent T2WI and DCE-MRI prior to prostate needle biopsy. The sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of T2WI and DCE-MRI to diagnose prostate cancer were evaluated. The relationship between Gleason score and prostate cancer detection by DCE-MRI was evaluated. Results: Prostate adenocarcinoma was histopathologically confirmed in 44/75 patients. DCE-MRI had significantly higher sensitivity, accuracy and NPV than T2WI. The detection rate of prostate cancer by DCE-MRI was significantly better for tumours with Gleason score 7-9 than for those Gleason score 4-6. Conclusion: DCE-MRI at 3.0T can significantly improve prostate cancer detection using simple visual diagnostic criteria, compared with T2WI.
引用
收藏
页码：1077 / 1084
页数：8
相关论文
共 30 条
  • [11] Histological characteristics of the index lesion in whole-mount radical prostatectomy specimens: implications for focal therapy
    Karavitakis, M.
    Winkler, M.
    Abel, P.
    Livni, N.
    Beckley, I.
    Ahmed, H. U.
    [J]. PROSTATE CANCER AND PROSTATIC DISEASES, 2011, 14 (01) : 46 - 52
  • [12] Simple models improve the discrimination of prostate cancers from the peripheral gland by T1-weighted dynamic MRI
    Kiessling, F
    Lichy, M
    Grobholz, R
    Heilmann, M
    Farhan, N
    Michel, MS
    Trojan, L
    Ederle, J
    Abel, U
    Kauczor, HU
    Semmler, W
    Delorme, S
    [J]. EUROPEAN RADIOLOGY, 2004, 14 (10) : 1793 - 1801
  • [13] Update of prostate magnetic resonance imaging at 3 T
    Kim, Chan Kyo
    Park, Byung Kwan
    [J]. JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2008, 32 (02) : 163 - 172
  • [14] Prostate Cancer Detection With 3 T MRI: Comparison of Diffusion-Weighted Imaging and Dynamic Contrast-Enhanced MRI in Combination With T2-Weighted Imaging
    Kitajima, Kazuhiro
    Kaji, Yasushi
    Fukabori, Yoshitatsu
    Yoshida, Ken-ichiro
    Suganuma, Narufumi
    Sugimura, Kazuro
    [J]. JOURNAL OF MAGNETIC RESONANCE IMAGING, 2010, 31 (03) : 625 - 631
  • [15] Analysis of Prostate DCE-MRI Comparison of Fast Exchange Limit and Fast Exchange Regimen Pharmacokinetic Models in the Discrimination of Malignant From Normal Tissue
    Lowry, Martin
    Zelhof, Bashar
    Liney, Gary P.
    Gibbs, Peter
    Pickles, Martin D.
    Turnbull, Lindsay W.
    [J]. INVESTIGATIVE RADIOLOGY, 2009, 44 (09) : 577 - 584
  • [16] Dynamic contrast enhanced MRI of prostate cancer: Correlation with morphology and tumour stage, histological grade and PSA
    Padhani, AR
    Gapinski, CJ
    Macvicar, DA
    Parker, GJ
    Suckling, J
    Revell, PB
    Leach, MO
    Dearnaley, DP
    Husband, JE
    [J]. CLINICAL RADIOLOGY, 2000, 55 (02) : 99 - 109
  • [17] Effects of Post Biopsy Digital Rectal Compression on Improving Prostate Cancer Staging Using Magnetic Resonance Imaging in Localized Prostate Cancer
    Park, Kyung Kgi
    Chung, Mun Su
    Chung, Soo Yoon
    Kim, Joo Hee
    Chung, Byung Ha
    [J]. YONSEI MEDICAL JOURNAL, 2013, 54 (01) : 81 - 86
  • [18] Combined magnetic resonance spectroscopy and dynamic contrast-enhanced imaging for prostate cancer detection
    Perdona, Sisto
    Di Lorenzo, Giuseppe
    Autorino, Riccardo
    Buonerba, Carlo
    De Sio, Marco
    Setola, Sergio Venanzio
    Fusco, Roberta
    Ronza, Francesco Michele
    Caraglia, Michele
    Ferro, Matteo
    Petrillo, Antonella
    [J]. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2013, 31 (06) : 761 - 765
  • [19] Focal prostatic atrophy: mimicry of prostatic cancer on TRUS and 3D-MRSI studies
    Prando, Adilson
    Billis, Athanase
    [J]. ABDOMINAL IMAGING, 2009, 34 (02): : 271 - 275
  • [20] Enhancement patterns of prostate cancer in dynamic MRI
    Preziosi, P
    Orlacchio, A
    Di Giambattista, G
    Di Renzi, P
    Bortolotti, L
    Fabiano, A
    Cruciani, E
    Pasqualetti, P
    [J]. EUROPEAN RADIOLOGY, 2003, 13 (05) : 925 - 930
123