Exploring the role of the bile acid receptor TGR5 in bile acid mediated obesity control: New insights from a CRISPR/Cas9 adipocyte model

被引：0
|
作者：
Teodoro, Joao Soeiro
Rolo, Anabela Pinto
Carvalho, Rui Albuquerque
Palmeira, Carlos Marques
机构：
[1] Univ Coimbra, CNC IBILI, Coimbra, Portugal
[2] Univ Coimbra, Dept Life Sci, Coimbra, Portugal
来源：
FREE RADICAL BIOLOGY AND MEDICINE | 2018年 / 120卷
关键词：
D O I：
10.1016/j.freeradbiomed.2018.04.466
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P-319
引用
收藏
页码：S141 / S141
页数：1
相关论文
共 50 条
  • [41] SECONDARY BILE ACIDS PROTECT AGAINST INTESTINAL INFLAMMATION VIA BILE ACID TGR5 RECEPTOR
    Sinha, Sidhartha R.
    Haileselassie, Yeneneh
    Linh Nguyen
    Tropini, Carolina
    Becker, Laren S.
    Sim, Davis
    Bittinger, Kyle
    Sonnenburg, Justin
    Habtezion, Aida
    GASTROENTEROLOGY, 2019, 156 (06) : S647 - S647
  • [42] TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload
    Bidault-Jourdainne, Valeska
    Merlen, Gregory
    Glenisson, Mathilde
    Doignon, Isabelle
    Garcin, Isabelle
    Pean, Noemie
    Boisgard, Raphael
    Ursic-Bedoya, Jose
    Serino, Matteo
    Ullmer, Christoph
    Humbert, Lydie
    Abdelrafee, Ahmed
    Golse, Nicolas
    Vibert, Eric
    Duclos-Vallee, Jean-Charles
    Rainteau, Dominique
    Tordjmann, Thierry
    JHEP REPORTS, 2021, 3 (02)
  • [43] Tongue bile acid receptor TGR5 is critically involved in preference for dietary lipids and obesity in mice: Role TGR5 in genetic polymorphism in human obese participants
    Sayed-Khan, Amira
    Bensalem, Adel
    Hichami, Aziz
    Oulamara, Hayet
    Khan, Naim Akhtar
    ACTA PHYSIOLOGICA, 2022, 236
  • [44] Bile Acid Receptor TGR5 Agonism Enhances Vascular Endothelial Barrier Function
    Kida, Taiki
    Murata, Takahisa
    Hori, Masatoshi
    Ozaki, Hiroshi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013, 121 : 72P - 72P
  • [45] The Anticancer Mechanism of Bile Acid Receptor TGR5 in Mouse Models of Lung Cancer
    Liu, X.
    Qi, F.
    Sun, H.
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 82 : 16 - 23
  • [46] The Bile Acid Receptor TGR5 (Gpbar-1) Acts as a Neurosteroid Receptor in Brain
    Keitel, Verena
    Goerg, Boris
    Bidmon, Hans J.
    Zemtsova, Irina
    Spomer, Lina
    Zilles, Karl
    Haeussinger, Dieter
    GLIA, 2010, 58 (15) : 1794 - 1805
  • [47] Membrane bile acid receptor TGR5 - a new target in the study of metabolic, inflammatory and neoplastic diseases
    Drapkina, O. M.
    Fomicheva, E. I.
    RATIONAL PHARMACOTHERAPY IN CARDIOLOGY, 2016, 12 (03) : 344 - 350
  • [48] The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic syndrome
    Vanesa Stepanov
    Karmen Stankov
    Momir Mikov
    BMC Pharmacology and Toxicology, 13 (Suppl 1)
  • [49] Taurochenodeoxycholic Acid Increases cAMP Content via Specially Interacting with Bile Acid Receptor TGR5
    Qi, Youchao
    Shi, Linkai
    Duan, Guozhen
    Ma, Yonggui
    Li, Peifeng
    MOLECULES, 2021, 26 (23):
  • [50] The Receptor TGR5 Protects the Liver From Bile Acid Overload During Liver Regeneration in Mice
    Pean, Noemie
    Doignon, Isabelle
    Garcin, Isabelle
    Besnard, Aurore
    Julien, Boris
    Liu, Bingkai
    Branchereau, Sophie
    Spraul, Anne
    Guettier, Catherine
    Humbert, Lydie
    Schoonjans, Kristina
    Rainteau, Dominique
    Tordjmann, Thierry
    HEPATOLOGY, 2013, 58 (04) : 1451 - 1460
12345