Exploring the role of the bile acid receptor TGR5 in bile acid mediated obesity control: New insights from a CRISPR/Cas9 adipocyte model

被引:0
|
作者
Teodoro, Joao Soeiro
Rolo, Anabela Pinto
Carvalho, Rui Albuquerque
Palmeira, Carlos Marques
机构
[1] Univ Coimbra, CNC IBILI, Coimbra, Portugal
[2] Univ Coimbra, Dept Life Sci, Coimbra, Portugal
关键词
D O I
10.1016/j.freeradbiomed.2018.04.466
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
P-319
引用
收藏
页码:S141 / S141
页数:1
相关论文
共 50 条
  • [1] Exploring the role of the bile acid receptor TGR5 in bile acid mediated obesity control: novel insights from a CRISPR/Cas9 adipocyte model
    Teodoro, J. S.
    Silva, R.
    Rolo, A. P.
    Carvalho, R. A.
    Palmeira, C. M.
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2018, 48 : 51 - 51
  • [2] Chenodeoxycholic Acid Has Non-Thermogenic, Mitodynamic Anti-Obesity Effects in an In Vitro CRISPR/Cas9 Model of Bile Acid Receptor TGR5 Knockdown
    Teodoro, Joao S.
    Machado, Ivo F.
    Castela, Ana C.
    Amorim, Joao A.
    Jarak, Ivana
    Carvalho, Rui A.
    Palmeira, Carlos M.
    Rolo, Anabela P.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)
  • [3] Mechanism of action of the bile acid receptor TGR5 in obesity
    Lun, Weijun
    Yan, Qihao
    Guo, Xinghua
    Zhou, Minchuan
    Bai, Yan
    He, Jincan
    Cao, Hua
    Che, Qishi
    Guo, Jiao
    Su, Zhengquan
    ACTA PHARMACEUTICA SINICA B, 2024, 14 (02) : 468 - 491
  • [4] Mechanism of action of the bile acid receptor TGR5 in obesity
    Weijun Lun
    Qihao Yan
    Xinghua Guo
    Minchuan Zhou
    Yan Bai
    Jincan He
    Hua Cao
    Qishi Che
    Jiao Guo
    Zhengquan Su
    Acta Pharmaceutica Sinica B, 2024, 14 (02) : 468 - 491
  • [5] The Role of TGR5 Receptor in Bile Acid-mediated Bone Metabolism
    Park, Hyojung
    Kim, Jung Hee
    Yang, Jae-Yeon
    Cho, Sun Wook
    Kim, Jung Hee
    Kim, Seung Hye
    Jang, Mi Gyeong
    Kim, Sang Wan
    Yim, Mijung
    Shin, Chan Soo
    JOURNAL OF BONE AND MINERAL RESEARCH, 2013, 28
  • [6] Bile acid mediated resistance to high-fat diet induced obesity is not mediated through bile acid (TGR5) receptor
    Michael, M. D.
    Coskun, T.
    Fitch, T. E.
    Briere, D. A.
    Cheng, C. C.
    Suen, C.
    DIABETOLOGIA, 2011, 54 : S276 - S276
  • [7] Hepatoprotective impact of the bile acid receptor TGR5
    Merlen, Gregory
    Bidault-Jourdainne, Valeska
    Kahale, Nicolas
    Glenisson, Mathilde
    Ursic-Bedoya, Jose
    Doignon, Isabelle
    Garcin, Isabelle
    Humbert, Lydie
    Rainteau, Dominique
    Tordjmann, Thierry
    LIVER INTERNATIONAL, 2020, 40 (05) : 1005 - 1015
  • [8] The Bile Acid Receptor TGR5 and Liver Regeneration
    Jourdainne, Valeska
    Pean, Noemie
    Doignon, Isabelle
    Humbert, Lydie
    Rainteau, Dominique
    Tordjmann, Thierry
    DIGESTIVE DISEASES, 2015, 33 (03) : 319 - 326
  • [9] THE ROLE OF THE BILE ACID RECEPTOR TGR5 IN ALZHEIMER'S DISEASE
    Ferrell, Jessica M.
    Boehme, Shannon
    Gilliland, Tricia
    Lin, Li
    Dengler-Crish, Christine M.
    Takahashi, Shogo
    Gonzalez, Frank J.
    Chiang, John Y. L.
    HEPATOLOGY, 2020, 72 : 229A - 230A
  • [10] The role of bile acid receptor TGR5 in regulating inflammatory signalling
    Ye, Daijiao
    He, Jiayao
    He, Xiaofei
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2024, 99 (04)