Discriminating between Anomalous Diffusion and Transient Behavior in Microheterogeneous Environments

被引：37

作者：

Berezhkovskii, Alexander M. ^{[1
,2
]}

Dagdug, Leonardo ^{[2
,3
]}

Bezrukov, Sergey M. ^{[1
]}

机构：

[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Phys Biol, NIH, Bethesda, MD USA

[2] NIH, Math & Stat Comp Lab, Div Computat Biosci, Ctr Informat Technol, Bethesda, MD 20892 USA

[3] Univ Autonoma Metropolitana Iztapalapa, Dept Fis, Iztapalapa, Mexico

来源：

BIOPHYSICAL JOURNAL | 2014年 / 106卷 / 02期

基金：

美国国家卫生研究院;

关键词：

SPINES;

D O I：

10.1016/j.bpj.2013.12.013

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Diffusion in macrohomogeneous and microheterogeneous media can be described as effective free diffusion only at sufficiently long times. At intermediate times, the mean-square displacement of a diffusing object shows a transient behavior that can be misinterpreted as anomalous subdiffusion. We discuss how to discriminate between the two.

引用

页码：L09 / L11

页数：3

共 11 条

[1] Validity of the diffusion equation at the atomic scale investigated via numerical simulations [J].

Adda, Y. ;

Philibert, J. ;

Pontikis, V. .

PHYSICAL REVIEW B, 2012, 85 (14)

[2] STRANGE KINETICS of single molecules in living cells [J].

Barkai, Eli ;

Garini, Yuval ;

Metzler, Ralf .

PHYSICS TODAY, 2012, 65 (08) :29-35

[3] Time and length scales for diffusion in liquids [J].

Berezhkovskii, A.M. ;

Sutmann, G. .

Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, 2002, 65 (06) :1-060201

[4] Analysis of phosphatidylinositol-4,5-bisphosphate signaling in cerebellar Purkinje spines [J].

Brown, Sherry-Ann ;

Morgan, Frank ;

Watras, James ;

Loew, Leslie M. .

BIOPHYSICAL JOURNAL, 2008, 95 (04) :1795-1812

[5] DIFFUSION IN EMBRYOGENESIS [J].

CRICK, F .

NATURE, 1970, 225 (5231) :420-&

[6] Transient diffusion in a tube with dead ends [J].

Dagdug, Leonardo ;

Berezhkovskii, Alexander M. ;

Makhnovskii, Yurii A. ;

Zitserman, Vladimir Yu. .

JOURNAL OF CHEMICAL PHYSICS, 2007, 127 (22)

[7] Diffusion in the presence of periodically spaced permeable membranes [J].

Dudko, OK ;

Berezhkovskii, AM ;

Weiss, GH .

JOURNAL OF CHEMICAL PHYSICS, 2004, 121 (22) :11283-11288

[8] Time-dependent diffusion in tubes with periodic partitions [J].

Makhnovskii, Yu A. ;

Berezhkovskii, A. M. ;

Zitserman, V. Yu. .

JOURNAL OF CHEMICAL PHYSICS, 2009, 131 (10)

[9] Anomalous diffusion in Purkinje cell dendrites caused by spines [J].

Santamaria, Fidel ;

Wils, Stefan ;

De Schutter, Erik ;

Augustine, George J. .

NEURON, 2006, 52 (04) :635-648

[10] Wanted: A Positive Control for Anomalous Subdiffusion [J].

Saxton, Michael J. .

BIOPHYSICAL JOURNAL, 2012, 103 (12) :2411-2422

← 1 2 →