Gold Approaches to Polycyclic Indole Alkaloids

被引：43

作者：

Barbour, P. Michael ^{[1
]}

Marholz, Laura J. ^{[1
]}

Chang, Le ^{[1
]}

Xu, Wenqing ^{[1
]}

Wang, Xiang ^{[1
]}

机构：

[1] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80309 USA

来源：

CHEMISTRY LETTERS | 2014年 / 43卷 / 05期

关键词：

STEREOCONTROLLED TOTAL-SYNTHESIS; ONE-POT SYNTHESIS; ALKYNYL INDOLES; CATALYSIS; REARRANGEMENT; ANNULATIONS; PLATINUM; ACCESS;

D O I：

10.1246/cl.131230

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Indole alkaloids are a highly diverse and ubiquitous family of natural products often identified in plants that have been used as traditional medicine for millennia. Because of their complex molecular architecture and relevance as potent pharmaceuticals, efficient methods for constructing these polycyclic skeletons are essential for their synthesis. Herein, we review recent developments in gold catalysis as a means toward the synthesis of many biologically important polycyclic indole alkaloids.

引用

页码：572 / 578

页数：7

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