Hemangioendothelioma: A rare vascular tumor in childhood and adolescence

Most vascular tumors occurring in children are benign. They are recognized by their ability to form angiomatous structures. In some instances, there is no clear-cut Line between a benign vascular tumor (or angioma) and a malignant vascular tumor (or angiosarcoma). The hemangioendothelioma is a rare tumor of vascular origin, involving bone or soft tissue, and represents 1% of all vascular neoplasms. Accurate diagnosis is critical In recommending the most appropriate therapy for each patient. The aim of this paper is to give a brief review of the literature of this rare entity, particularly in childhood and adolescence.