Long-Term Efficacy of Computerized Cognitive Training Among Survivors of Childhood Cancer: A Single-Blind Randomized Controlled Trial

被引：56

作者：

Conklin, Heather M. ^{[1
]}

Ashford, Jason M. ^{[1
]}

Clark, Kellie N. ^{[1
]}

Martin-Elbahesh, Karen ^{[1
]}

Hardy, Kristina K. ^{[2
,3
]}

Merchant, Thomas E. ^{[4
]}

Ogg, Robert J. ^{[5
]}

Jeha, Sima ^{[6
]}

Huang, Lu ^{[7
]}

Zhang, Hui ^{[7
]}

机构：

[1] St Jude Childrens Res Hosp, Dept Psychol, 332 N Lauderdale St, Memphis, TN 38105 USA

[2] Childrens Natl Med Ctr, Ctr Neurosci & Behav Med, Neuropsychol Div, Washington, DC 20010 USA

[3] George Washington Univ, Sch Med, Dept Psychiat & Behav Sci, Washington, DC 20052 USA

[4] St Jude Childrens Res Hosp, Dept Radiat Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA

[5] St Jude Childrens Res Hosp, Div Translat Imaging, 332 N Lauderdale St, Memphis, TN 38105 USA

[6] St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA

[7] St Jude Childrens Res Hosp, Dept Biostat, 332 N Lauderdale St, Memphis, TN 38105 USA

来源：

JOURNAL OF PEDIATRIC PSYCHOLOGY | 2017年 / 42卷 / 02期

基金：

美国国家卫生研究院;

关键词：

brain tumor; computerized cognitive training; leukemia; pediatric; working memory; PLACEBO-CONTROLLED TRIAL; WORKING-MEMORY; CHILDREN; METHYLPHENIDATE; ATTENTION; LEUKEMIA; DEFICITS; SKILLS; LEADS;

D O I：

10.1093/jpepsy/jsw057

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Objective To investigate the long-term efficacy of computerized cognitive training in improving cognitive outcomes among childhood cancer survivors. Methods Sixty-eight survivors of childhood acute lymphoblastic leukemia (ALL) or brain tumor (BT) were randomly assigned to computerized cognitive intervention (23 ALL/11 BT, age = 12.21 + 2.47) or a waitlist control group (24 ALL/10 BT, age = 11.82 + 2.42). Cognitive assessments were completed pre-, immediately post-, and 6 months postintervention. Results A prior report showed training led to immediate improvement in working memory, attention and processing speed. In the current study, piecewise linear mixed effects modeling revealed that working memory and processing speed were unchanged from immediate to 6 months postintervention (intervention beta = -.04 to .01, p = .26 to .95; control beta= -.06 to .01, p = .23-.97), but group differences on an attention measure did not persist. Conclusion Cognitive benefits are maintained 6 months following computerized cognitive training, adding to potential clinical utility of this intervention approach.

引用

页码：220 / 231

页数：12

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