New A-ring lactone triterpenoid saponins from the roots of Platycodon grandiflorum

被引:32
作者
Fu, Wen-Wei
Shimizu, Noriko
Takeda, Tadahiro
Dou, De-Qiang
Chen, Baohui
Pei, Yue-Hu
Chen, Ying-Jie
机构
[1] Kyoritsu Univ Pharm, Minato Ku, Tokyo 1058512, Japan
[2] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat, Shenyang 110016, Peoples R China
关键词
Platycodon grandiflorum; saponin; platycogenic acid A lactone; platycoside M-1; platycoside M-2; platycoside M-3;
D O I
10.1248/cpb.54.1285
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Three new A-ring lactone triterpenoid saponins, platycoside M-1 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone], platycoside M-2 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone 28-O-alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranoside], and platycoside M-3 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone 28-O-beta-D-xylopyranosyl-(1 -> 4)-alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranoside], were isolated from the roots of Platycodon grandiflorum A. DC. Their chemical structures were elucidated on the basis of their spectral data and chemical evidence.
引用
收藏
页码:1285 / 1287
页数:3
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