Effective pain therapy can improve the survival of patients with pancreatic cancer

被引:2
|
作者
Ozcan, Sibel [1 ]
Akin, Sevim [1 ]
Yildiz Altun, Aysun [1 ]
Bolat, Esef [1 ]
Ates Onal, Selami [2 ]
机构
[1] Firat Univ, Dept Anaesthesiol & Reanimat, Fac Med, Elazig, Turkey
[2] VM Med Pk Pendik Hosp, Pain Clin, Dept Anaesthesiologyand Reanimat, Istanbul, Turkey
来源
AGRI-THE JOURNAL OF THE TURKISH SOCIETY OF ALGOLOGY | 2019年 / 31卷 / 03期
关键词
Survival; pancreatic cancer; pain; visual analog scale; CELIAC PLEXUS NEUROLYSIS; ADENOCARCINOMA; MANAGEMENT; PLACEBO;
D O I
10.14744/agri.2019.61224
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: In this study, characteristics and analgesic treatment of patients with pancreatic cancer who applied to the algology clinic were evaluated. Methods: Demographic characteristics, pathologic diagnosis, metastasis, cancer treatment, and analgesic interventions in 60 patients with pancreatic cancer, referred to the algology clinic, were examined. Results: The application time of the patients to the clinic was 3.9 +/- 0.92 months after the diagnosis, and the visual analog scale (VAS) was 6.96 +/- 0.11 at the initial assessment. According to the analgesic step ladder protocol, a nonopiod + weak opioid + strong opioid (transdermal) were applied in 58.33%, a nonopioid + weak opioid + strong opiod (oral) in 5%, and nonopiod + weak opioid in 36.66% of the patients. Adjuvant pain medications were used in 68.33% of the patients (benzodiazepine, 80.48%; antidepressant, 19.51%), while no adjuvant was used in 31.66% of the patients. While the mean survival time for patients with pancreatic cancer changed from 3 to 6 months, it was 8.48 +/- 7.46 months for patients who applied to the pain clinic. Conclusion: Abdominal pain in pancreatic cancer is the most common symptom that negatively affects the quality of life. A good analgesia improves the survival, while pain decreases the survival. The results of the present study demonstrated that the survival of the patients with metastatic pancreatic cancer who received effective pain therapy in the algology clinic may be longer.
引用
收藏
页码:145 / 149
页数:5
相关论文
共 50 条
  • [1] Cannabinoids in pancreatic cancer:: Correlation with survival and pain
    Michalski, Christoph W.
    Oti, Florian E.
    Erkan, Mert
    Saulitmaite, Danguole
    Bergmann, Frank
    Pacher, Pal
    Batkai, Sandor
    Mueller, Michael W.
    Giese, Nathalia A.
    Friess, Helmut
    Kleeff, Joerg
    INTERNATIONAL JOURNAL OF CANCER, 2008, 122 (04) : 742 - 750
  • [2] Can Naloxegol Therapy Improve Quality of Life in Patients with Advanced Cancer?
    Ostan, Rita
    Gambino, Giuseppe
    Malavasi, Italo
    Ronga, Gianluca
    Solipaca, Maria
    Spunghi, Michela
    Varani, Silvia
    Pannuti, Raffaella
    Ruggeri, Enrico
    CANCERS, 2021, 13 (22)
  • [3] Does extended lymphadenectomy improve survival of pancreatic cancer patients
    Popiela, T
    Kedra, B
    Sierzega, M
    ACTA CHIRURGICA BELGICA, 2002, 102 (02) : 78 - 82
  • [4] Magic of a Common Sugar Pill in Cancer: Can Metformin Raise Survival in Pancreatic Cancer Patients?
    Gyawali, Mallika
    Venkatesan, Nanditha
    Ogeyingbo, Opemipo D.
    Bhandari, Renu
    Botleroo, Rinky A.
    Kareem, Roaa
    Ahmed, Rowan
    Elshaikh, Abeer O.
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (08)
  • [5] Postoperative complications and survival rates for pancreatic cancer patients
    Katuchova, Jana
    Bober, Juraj
    Radonak, Jozef
    WIENER KLINISCHE WOCHENSCHRIFT, 2011, 123 (3-4) : 94 - 99
  • [6] Prognostic Factors for Survival in Patients With Unresectable Pancreatic Cancer
    Weber, Andreas
    Kehl, Victoria
    Mittermeyer, Tobias
    Herberich, Esther
    Roethling, Nadine
    Schmid, Roland M.
    Prinz, Christian
    PANCREAS, 2010, 39 (08) : 1247 - 1253
  • [7] Can erythropoietin therapy improve survival?
    Glaspy, J
    Dunst, J
    ONCOLOGY, 2004, 67 : 5 - 11
  • [8] Development and Validation of a Survival Prediction Model for Patients With Pancreatic Cancer
    James, Paul D.
    Almousawi, Fatema
    Salim, Misbah
    Khan, Rishad
    Tanuseputro, Peter
    Hsu, Amy T.
    Coburn, Natalie
    Alabdulkarim, Balqis
    Talarico, Robert
    Gayowsky, Anastasia
    Webber, Colleen
    Seow, Hsien
    Sutradhar, Rinku
    CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 2025, 16 (01)
  • [9] Diagnostic delay does not influence survival of pancreatic cancer patients
    Stornello, Caterina
    Archibugi, Livia
    Stigliano, Serena
    Vanella, Giuseppe
    Graglia, Benedetta
    Capalbo, Carlo
    Nigri, Giuseppe
    Capurso, Gabriele
    UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, 2020, 8 (01) : 81 - 90
  • [10] Induction Therapy in Localized Pancreatic Cancer
    Shaib, Walid L.
    Sayegh, Layal
    Zhang, Chao
    Belalcazar, Astrid
    Ip, Andrew
    Alese, Olatunji B.
    Akce, Mehmet
    Wu, Christina
    Qu, Yuesheng
    Maithel, Shishir K.
    Kooby, David
    Cardona, Kenneth
    Sarmeinto, Juan M.
    El-Rayes, Bassel E.
    PANCREAS, 2019, 48 (07) : 913 - 919