Multiple pregnancies following assisted reproductive technologies - A happy consequence or double trouble?

被引:47
作者
Murray, S. R. [1 ]
Norman, J. E. [2 ]
机构
[1] Royal Infirm Edinburgh NHS Trust, Simpson Ctr Reprod Hlth, Edinburgh EH16 4TJ, Midlothian, Scotland
[2] Queens Med Res Inst, MRC Ctr Reprod Hlth, Edinburgh, Midlothian, Scotland
基金
英国医学研究理事会;
关键词
Assisted reproductive techniques; Multifetal pregnancy; Multifetal pregnancy reduction; Multiple pregnancy; Single embryo transfer; IN-VITRO FERTILIZATION; SINGLE EMBRYO-TRANSFER; PERINATAL OUTCOMES; NEONATAL OUTCOMES; FETAL REDUCTION; CEREBRAL-PALSY; INCREASED RISK; TWINS; INFERTILITY; BIRTHS;
D O I
10.1016/j.siny.2014.03.001
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The association between assisted reproduction technologies (ART) and multiple pregnancy is well-established, with a multiple birth rate of 24% in ART pregnancies. Multiple pregnancy is associated with significantly increased maternal and perinatal morbidity and mortality, as well as increased costs to the National Health Service. Evidence relating to the obstetric outcomes of ART twins versus naturally conceived twins is discussed in this review. Methods to reduce the risk of multiple births including elective single embryo transfer and multifetal pregnancy reduction are also discussed. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:222 / 227
页数:6
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