Palladium-catalyzed annulation of benzynes with N-substituted-N-(2-halophenyl)formamides: synthesis of phenanthridinones

被引：31

作者：

Yang, Yuan ^{[1
]}

Huang, Hui ^{[1
]}

Wu, Lijun ^{[1
]}

Liang, Yun ^{[1
,2
]}

机构：

[1] Hunan Normal Univ, Natl & Local Joint Engn Lab New Petrochem Mat & F, Key Lab Chem Biol & Tradit Chinese Med Res, Minist Educ, Changsha 410081, Hunan, Peoples R China

[2] Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 29期

关键词：

EFFICIENT SYNTHESIS; CARBON-CARBON; ARYNES; ARYL; DERIVATIVES; ARYLATION; ANALOGS; ARENES; POTENT; ACID;

D O I：

10.1039/c4ob00997e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient procedure for the synthesis of N-substituted phenanthridinones via palladium-catalyzed annulation of benzynes with N-substituted-N-(2-halophenyl) formamides has been developed. This methodology constructs two new C-C bonds via an arylation/annulation process, and provides the desired products in good yields.

引用

页码：5351 / 5355

页数：5