Palladium-catalyzed annulation of benzynes with N-substituted-N-(2-halophenyl)formamides: synthesis of phenanthridinones

被引：31
|
作者：
Yang, Yuan [1 ]
Huang, Hui [1 ]
Wu, Lijun [1 ]
Liang, Yun [1 ,2 ]
机构：
[1] Hunan Normal Univ, Natl & Local Joint Engn Lab New Petrochem Mat & F, Key Lab Chem Biol & Tradit Chinese Med Res, Minist Educ, Changsha 410081, Hunan, Peoples R China
[2] Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 29期
关键词：
EFFICIENT SYNTHESIS; CARBON-CARBON; ARYNES; ARYL; DERIVATIVES; ARYLATION; ANALOGS; ARENES; POTENT; ACID;
D O I：
10.1039/c4ob00997e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel and efficient procedure for the synthesis of N-substituted phenanthridinones via palladium-catalyzed annulation of benzynes with N-substituted-N-(2-halophenyl) formamides has been developed. This methodology constructs two new C-C bonds via an arylation/annulation process, and provides the desired products in good yields.
引用
收藏
页码：5351 / 5355
页数：5
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