The prognostic significance of early remission of positive symptoms in first treated psychosis

被引：12
作者：
Norman, Ross M. G. [1 ,2 ]
Manchanda, Rahul [1 ,2 ]
Windell, Deborah [2 ]
机构：
[1] Univ Western Ontario, Dept Psychiat, London Hlth Sci Ctr, London, ON N6A 5W9, Canada
[2] London Hlth Sci Ctr, Prevent & Early Intervent Program Psychoses PEPP, London, ON N6A 5W9, Canada
来源：
PSYCHIATRY RESEARCH | 2014年 / 218卷 / 1-2期
关键词：
Schizophrenia; Outcomes; Prognosis; Functioning; Employment; Disability; 1ST-EPISODE PSYCHOSIS; ANTIPSYCHOTIC MEDICATION; UNTREATED PSYCHOSIS; TREATMENT RESPONSE; SCHIZOPHRENIA; DURATION; LIFE; PREDICTORS; RECOVERY; CRITERIA;
D O I：
10.1016/j.psychres.2014.04.006
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
We examine the relationship between achieving remission of positive symptoms within 3 months in first episode psychosis and outcomes 5 years later. Time to remission of positive symptoms, other early characteristics and 5 year outcomes were assessed in a prospective study of 132 patients being treated for the first time for a psychotic disorder. Just under 60% of patients showed remission of positive symptoms within 3 months. In comparison to later remitters, they showed lower levels of positive symptoms, greater likelihood of competitive employment and less likelihood of collecting a disability pension at 5 years. Earlier remission of positive symptoms may have prognostic significance for longer term outcomes. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：44 / 47
页数：4
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