Idiopathic Intracranial Hypertension and Obesity

被引：77
作者：
Andrews, Laura E. [2 ]
Liu, Grant T. [3 ,4 ]
Ko, Melissa W. [1 ,2 ]
机构：
[1] SUNY Upstate Med Univ, Univ Hlth Care Ctr, Dept Neurol, Syracuse, NY 13210 USA
[2] SUNY Upstate Med Univ, Syracuse, NY 13210 USA
[3] Univ Penn, Perelman Sch Med, Dept Neurol, Philadelphia, PA 19104 USA
[4] Univ Penn, Perelman Sch Med, Dept Ophthalmol, Philadelphia, PA 19104 USA
来源：
HORMONE RESEARCH IN PAEDIATRICS | 2014年 / 81卷 / 04期
关键词：
Idiopathic intracranial hypertension; pediatric; Pseudotumor cerebri; Obesity; Weight gain; Recurrence; EXTREME CHILDHOOD OBESITY; GROWTH-HORMONE TREATMENT; PSEUDOTUMOR CEREBRI; WEIGHT-GAIN; DESCRIPTIVE EPIDEMIOLOGY; PRESENTING FEATURES; CLINICAL-FEATURES; RISK-FACTOR; WOMEN; PRESSURE;
D O I：
10.1159/000357730
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Idiopathic intracranial hypertension (IIH), also known as primary pseudotumor cerebri syndrome (PTCS), is a condition of unknown etiology which affects primarily overweight, reproductive-aged women and causes increased intracranial pressure (ICP). This review discusses the recently revised diagnostic criteria for PTCS for adults and children. Additionally, the role of obesity in the epidemiology, etiology, and management of IIH as well as the current knowledge of obesity profiles and markers in IIH are reviewed. We also highlight the emerging, unifying theory of the neuroendocrine effects on the mineralocorticoid receptor to explain a possible mechanism for the increased cerebrospinal fluid production and ICP in secondary PTCS. (C) 2014 S. Karger AG, Basel
引用
收藏
页码：217 / 225
页数：9
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